Patterns of inflammation and immune activation by coreceptor use in people living with HIV-1
IntroductionHuman immunodeficiency virus type 1 (HIV-1) utilizes either the CCR5 (R5) or CXCR4 (X4) coreceptor for host cell entry. Coreceptor switching from R5 to X4 and elevated immune activation have been associated with disease progression. X4-trop…