Breaking the heterogeneity barrier: a robust prognostic signature for survival stratification and immune profiling in triple-negative breast cancer

BackgroundTriple-negative breast cancer (TNBC), a highly heterogeneous breast cancer subtype, poses significant challenges to human health. Intra-tumor heterogeneity (ITH) limits the reliability of conventional prognostic models.MethodsUsing multi-regi…

Intra-tumor heterogeneity-resistant gene signature predicts prognosis and immune infiltration in breast cancer

BackgroundBreast cancer (BC) remains a significant threat to human health, with substantial variations in prognosis and treatment responses. Intra-tumor heterogeneity (ITH) presents a critical challenge in developing reliable prognostic models.MethodsT…

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nginx/1.24.0 (Ubuntu)