Lrba participates in the differentiation of IgA+ B lymphocytes through TGFβR signaling
IntroductionLrba is a cytoplasmic protein involved in vesicular trafficking. Lrba-deficient (Lrba-/-) mice exhibit substantially higher levels of IgA in both serum and feces than wild-type (WT) mice. Transforming growth factor β1 (TGFβ1) and its recept…