Integrative miRNA-mRNA profiling uncovers mechanisms of belimumab action in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by autoreactive B cells and characterized by the production of pathogenic autoantibodies. Belimumab, an anti-BAFF monoclonal antibody, has demonstrated efficacy in reducing dise…