ObjectiveDiabetes mellitus combined with nonalcoholic fatty liver disease is a prevalent and intricate metabolic disorder that presents a significant global health challenge, imposing economic and emotional burdens on society and families. An in-depth …

IntroductionGestational diabetes mellitus (GDM) and preeclampsia are prevalent pregnancy complications that threaten maternal and infant health while imposing substantial socioeconomic burdens. Although several interventions exist, shortcomings in indi…

BackgroundHematopoietic progenitor kinase 1 (HPK1) is a member of the mitogen-activated protein kinase kinase kinase kinase (MAP4K) family. It has been reported that HPK1 negatively regulates the activation of T cells. Several compounds have been devel…