PSMD14 drives lung adenocarcinoma progression through HMMR stabilization and dual activation of TGF-β/Smad and PI3K/AKT/mTOR signaling
BackgroundLung adenocarcinoma (LUAD) represents a major subtype of non-small cell lung cancer with limited therapeutic options. While the ubiquitin-proteasome system has been implicated in cancer pathogenesis, the specific role of deubiquitinating enzy…