{"id":16784,"date":"2024-09-29T01:17:29","date_gmt":"2024-09-28T23:17:29","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2024\/09\/29\/powerful-microscopy-technologies-decode-spatially-organized-cellular-networks-that-drive-response-to-immunotherapy-in-humans-2\/"},"modified":"2024-09-29T01:19:25","modified_gmt":"2024-09-28T23:19:25","slug":"powerful-microscopy-technologies-decode-spatially-organized-cellular-networks-that-drive-response-to-immunotherapy-in-humans-2","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2024\/09\/29\/powerful-microscopy-technologies-decode-spatially-organized-cellular-networks-that-drive-response-to-immunotherapy-in-humans-2\/","title":{"rendered":"Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans"},"content":{"rendered":"<div>\n<p>Curr Opin Immunol. 2024 Sep 13;91:102463. doi: 10.1016\/j.coi.2024.102463. Online ahead of print.<\/p>\n<p>ABSTRACT<\/p>\n<p>In tumors, immune cells organize into networks of different sizes and composition, including complex tertiary lymphoid structures and recently identified networks centered around the chemokines CXCL9\/10\/11 and CCL19. New commercially available highly multiplexed microscopy using cyclical RNA in situ hybridization and antibody-based approaches have the potential to establish the organization of the immune response in human tissue and serve as a foundation for future immunology research.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39277910\/?utm_source=Chrome&amp;utm_medium=rss&amp;utm_content=8900118&amp;ff=20240928191559&amp;v=2.18.0.post9+e462414\">39277910<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.coi.2024.102463\">10.1016\/j.coi.2024.102463<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Curr Opin Immunol. 2024 Sep 13;91:102463. doi: 10.1016\/j.coi.2024.102463. Online ahead of print. ABSTRACT In tumors, immune cells organize into networks of different sizes and composition, including complex tertiary lymphoid structures and recently identified networks centered around the chemokines CXCL9\/10\/11 and CCL19. New commercially available highly multiplexed microscopy using cyclical RNA in situ hybridization and antibody-based &#8230; <a title=\"Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2024\/09\/29\/powerful-microscopy-technologies-decode-spatially-organized-cellular-networks-that-drive-response-to-immunotherapy-in-humans-2\/\" aria-label=\"Read more about Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59,42],"tags":[],"class_list":["post-16784","post","type-post","status-publish","format-standard","hentry","category-current-opinion-in-immunology","category-publicaciones"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/16784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=16784"}],"version-history":[{"count":1,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/16784\/revisions"}],"predecessor-version":[{"id":16789,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/16784\/revisions\/16789"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=16784"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=16784"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=16784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}