{"id":16900,"date":"2024-09-29T10:07:00","date_gmt":"2024-09-29T08:07:00","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2024\/09\/29\/feeding-the-wrath-with-myelin-sourav-ghosh\/"},"modified":"2024-09-29T10:07:00","modified_gmt":"2024-09-29T08:07:00","slug":"feeding-the-wrath-with-myelin-sourav-ghosh","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2024\/09\/29\/feeding-the-wrath-with-myelin-sourav-ghosh\/","title":{"rendered":"Feeding the wrath with myelin. Sourav Ghosh"},"content":{"rendered":"<div>\n<p>Trends Immunol. 2024 Sep 27:S1471-4906(24)00212-6. doi: 10.1016\/j.it.2024.09.004. Online ahead of print.<\/p>\n<p>ABSTRACT<\/p>\n<p>Kloosterman and colleagues studied molecular and cellular changes during radiation therapy and disease recurrence across molecular subtypes of glioblastoma. They uncovered a distinct immune-cancer cell metabolic crosstalk during proneural\/oligodendrocyte progenitor cell-like to mesenchymal-like transition, wherein macrophages feed on cholesterol-rich myelin debris to provide lipids to mesenchymal tumor cells, thereby fueling glioblastoma growth.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39341708\/?utm_source=Chrome&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20240929040651&amp;v=2.18.0.post9+e462414\">39341708<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2024.09.004\">10.1016\/j.it.2024.09.004<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2024 Sep 27:S1471-4906(24)00212-6. doi: 10.1016\/j.it.2024.09.004. Online ahead of print. ABSTRACT Kloosterman and colleagues studied molecular and cellular changes during radiation therapy and disease recurrence across molecular subtypes of glioblastoma. They uncovered a distinct immune-cancer cell metabolic crosstalk during proneural\/oligodendrocyte progenitor cell-like to mesenchymal-like transition, wherein macrophages feed on cholesterol-rich myelin debris to provide &#8230; <a title=\"Feeding the wrath with myelin. Sourav Ghosh\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2024\/09\/29\/feeding-the-wrath-with-myelin-sourav-ghosh\/\" aria-label=\"Read more about Feeding the wrath with myelin. Sourav Ghosh\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-16900","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/16900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=16900"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/16900\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=16900"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=16900"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=16900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}