{"id":19755,"date":"2024-11-22T06:49:54","date_gmt":"2024-11-22T05:49:54","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2024\/11\/22\/please-dont-go-retinoic-acid-retains-tissue-specific-memory-michal-a-stanczak\/"},"modified":"2024-11-22T06:49:54","modified_gmt":"2024-11-22T05:49:54","slug":"please-dont-go-retinoic-acid-retains-tissue-specific-memory-michal-a-stanczak","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2024\/11\/22\/please-dont-go-retinoic-acid-retains-tissue-specific-memory-michal-a-stanczak\/","title":{"rendered":"Please don&#8217;t go: retinoic acid &#8216;retains&#8217; tissue-specific memory. Michal A Stanczak"},"content":{"rendered":"<div>\n<p>Trends Immunol. 2024 Nov 20:S1471-4906(24)00276-X. doi: 10.1016\/j.it.2024.11.005. Online ahead of print.<\/p>\n<p>ABSTRACT<\/p>\n<p>Tissue-resident memory (TRM) T cells not only control infection and cancer, but also contribute to inflammatory disease. In a recent study, Obers et al. demonstrate that retinoic acid (RA) and TGF-\u03b2 direct TRM residency in mice, with RA uniquely retaining cells in the intestine by limiting migration. This discovery highlights the potential for harnessing local residency cues to enhance tissue-specific TRM responses.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39572339\/?utm_source=WordPress&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20241122004953&amp;v=2.18.0.post9+e462414\">39572339<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2024.11.005\">10.1016\/j.it.2024.11.005<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2024 Nov 20:S1471-4906(24)00276-X. doi: 10.1016\/j.it.2024.11.005. Online ahead of print. ABSTRACT Tissue-resident memory (TRM) T cells not only control infection and cancer, but also contribute to inflammatory disease. In a recent study, Obers et al. demonstrate that retinoic acid (RA) and TGF-\u03b2 direct TRM residency in mice, with RA uniquely retaining cells in the &#8230; <a title=\"Please don&#8217;t go: retinoic acid &#8216;retains&#8217; tissue-specific memory. Michal A Stanczak\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2024\/11\/22\/please-dont-go-retinoic-acid-retains-tissue-specific-memory-michal-a-stanczak\/\" aria-label=\"Read more about Please don&#8217;t go: retinoic acid &#8216;retains&#8217; tissue-specific memory. Michal A Stanczak\">Read more<\/a><\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-19755","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/19755","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=19755"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/19755\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=19755"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=19755"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=19755"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}