{"id":19785,"date":"2024-11-28T08:10:40","date_gmt":"2024-11-28T07:10:40","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2024\/11\/28\/breaking-down-iga-tomasiella-immunophila-enlightens-microbiome-immune-interactions-duncan-b-sutherland\/"},"modified":"2024-11-28T08:10:40","modified_gmt":"2024-11-28T07:10:40","slug":"breaking-down-iga-tomasiella-immunophila-enlightens-microbiome-immune-interactions-duncan-b-sutherland","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2024\/11\/28\/breaking-down-iga-tomasiella-immunophila-enlightens-microbiome-immune-interactions-duncan-b-sutherland\/","title":{"rendered":"Breaking down IgA: Tomasiella immunophila enlightens microbiome-immune interactions. Duncan B Sutherland"},"content":{"rendered":"<div>\n<p>Trends Immunol. 2024 Nov 26:S1471-4906(24)00274-6. doi: 10.1016\/j.it.2024.11.003. Online ahead of print.<\/p>\n<p>ABSTRACT<\/p>\n<p>The recent discovery by Lu and colleagues of Tomasiella immunophila, a bacterium that degrades IgA, offers insights into microbial influences on mucosal immunity and evolutionary immune trade-offs. By modulating IgA titers, T. immunophila influences the dynamic interactions and balance between the host and pathogen. This has implications for immune health, microbiome research, and therapeutics.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39603890\/?utm_source=WordPress&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20241128021039&amp;v=2.18.0.post9+e462414\">39603890<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2024.11.003\">10.1016\/j.it.2024.11.003<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2024 Nov 26:S1471-4906(24)00274-6. doi: 10.1016\/j.it.2024.11.003. Online ahead of print. ABSTRACT The recent discovery by Lu and colleagues of Tomasiella immunophila, a bacterium that degrades IgA, offers insights into microbial influences on mucosal immunity and evolutionary immune trade-offs. By modulating IgA titers, T. immunophila influences the dynamic interactions and balance between the host and &#8230; <a title=\"Breaking down IgA: Tomasiella immunophila enlightens microbiome-immune interactions. Duncan B Sutherland\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2024\/11\/28\/breaking-down-iga-tomasiella-immunophila-enlightens-microbiome-immune-interactions-duncan-b-sutherland\/\" aria-label=\"Read more about Breaking down IgA: Tomasiella immunophila enlightens microbiome-immune interactions. Duncan B Sutherland\">Read more<\/a><\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-19785","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/19785","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=19785"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/19785\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=19785"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=19785"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=19785"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}