{"id":19844,"date":"2024-12-18T00:48:07","date_gmt":"2024-12-17T23:48:07","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2024\/12\/18\/unveiling-the-role-of-resident-memory-t-cells-in-psoriasisjuan-saavedra-almarza-on-17-de-december-de-2024-at-1100\/"},"modified":"2024-12-18T00:48:07","modified_gmt":"2024-12-17T23:48:07","slug":"unveiling-the-role-of-resident-memory-t-cells-in-psoriasisjuan-saavedra-almarza-on-17-de-december-de-2024-at-1100","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2024\/12\/18\/unveiling-the-role-of-resident-memory-t-cells-in-psoriasisjuan-saavedra-almarza-on-17-de-december-de-2024-at-1100\/","title":{"rendered":"Unveiling the Role of Resident Memory T Cells in Psoriasis\u200bJuan Saavedra-Almarza   on 17 de December de 2024 at 11:00"},"content":{"rendered":"<div>\n<p>J Leukoc Biol. 2024 Dec 17:qiae254. doi: 10.1093\/jleuko\/qiae254. Online ahead of print.<\/p>\n<p>ABSTRACT<\/p>\n<p>Psoriasis is a chronic inflammatory skin disease characterized by periods of remission and relapse. In this pathology, keratinocytes, dendritic cells, and different subpopulations of T cells are critical to developing psoriatic lesions. Although current treatments can reduce symptoms, they reappear in previously injured areas months after stopping treatment. Evidence has pointed out that besides T helper 17 cells, other T cell subsets may be involved in relapses. This review focuses on the leading evidence linking resident memory T cells and P2X7 receptor to psoriasis&#8217; pathogenesis and their role in this pathology. Finally, we discuss some of the most widely used experimental murine models and novel strategies to investigate further the role of resident memory T cells in psoriasis.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39689031\/?utm_source=WordPress&amp;utm_medium=rss&amp;utm_content=8405628&amp;ff=20241217184807&amp;v=2.18.0.post9+e462414\">39689031<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1093\/jleuko\/qiae254\">10.1093\/jleuko\/qiae254<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>J Leukoc Biol. 2024 Dec 17:qiae254. doi: 10.1093\/jleuko\/qiae254. Online ahead of print. ABSTRACT Psoriasis is a chronic inflammatory skin disease characterized by periods of remission and relapse. In this pathology, keratinocytes, dendritic cells, and different subpopulations of T cells are critical to developing psoriatic lesions. Although current treatments can reduce symptoms, they reappear in previously &#8230; <a title=\"Unveiling the Role of Resident Memory T Cells in Psoriasis\u200bJuan Saavedra-Almarza   on 17 de December de 2024 at 11:00\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2024\/12\/18\/unveiling-the-role-of-resident-memory-t-cells-in-psoriasisjuan-saavedra-almarza-on-17-de-december-de-2024-at-1100\/\" aria-label=\"Read more about Unveiling the Role of Resident Memory T Cells in Psoriasis\u200bJuan Saavedra-Almarza   on 17 de December de 2024 at 11:00\">Read more<\/a><\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86,42],"tags":[],"class_list":["post-19844","post","type-post","status-publish","format-standard","hentry","category-journal-of-leukocyte-biology","category-publicaciones"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/19844","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=19844"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/19844\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=19844"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=19844"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=19844"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}