{"id":28403,"date":"2025-03-29T21:49:56","date_gmt":"2025-03-29T20:49:56","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2025\/03\/29\/deciphering-sars-cov-2-evolution-under-antibody-immune-pressure-fanchong-jian\/"},"modified":"2025-03-29T21:49:56","modified_gmt":"2025-03-29T20:49:56","slug":"deciphering-sars-cov-2-evolution-under-antibody-immune-pressure-fanchong-jian","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2025\/03\/29\/deciphering-sars-cov-2-evolution-under-antibody-immune-pressure-fanchong-jian\/","title":{"rendered":"Deciphering SARS-CoV-2 evolution under antibody immune pressure. Fanchong Jian"},"content":{"rendered":"<div>\n<p><b>Trends Immunol<\/b>. 2025 Mar 27:S1471-4906(25)00076-6. doi: 10.1016\/j.it.2025.03.002. Online ahead of print.<\/p>\n<p><b>ABSTRACT<\/b><\/p>\n<p>The ongoing evolution of SARS-CoV-2 poses significant challenges to existing neutralizing antibodies and vaccines through immune escape mutations. By leveraging genomic surveillance and antibody deep mutational scanning (DMS) data, Raharinirina and colleagues developed a computational framework to elucidate region-specific SARS-CoV-2 variant dynamics and predict evolutionary trends under population immunity.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40155215\/?utm_source=WordPress&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20250329164955&amp;v=2.18.0.post9+e462414\">40155215<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2025.03.002\">10.1016\/j.it.2025.03.002<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2025 Mar 27:S1471-4906(25)00076-6. doi: 10.1016\/j.it.2025.03.002. Online ahead of print. ABSTRACT The ongoing evolution of SARS-CoV-2 poses significant challenges to existing neutralizing antibodies and vaccines through immune escape mutations. By leveraging genomic surveillance and antibody deep mutational scanning (DMS) data, Raharinirina and colleagues developed a computational framework to elucidate region-specific SARS-CoV-2 variant dynamics and &#8230; <a title=\"Deciphering SARS-CoV-2 evolution under antibody immune pressure. Fanchong Jian\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2025\/03\/29\/deciphering-sars-cov-2-evolution-under-antibody-immune-pressure-fanchong-jian\/\" aria-label=\"Read more about Deciphering SARS-CoV-2 evolution under antibody immune pressure. Fanchong Jian\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-28403","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/28403","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=28403"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/28403\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=28403"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=28403"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=28403"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}