{"id":33552,"date":"2025-05-28T06:47:10","date_gmt":"2025-05-28T04:47:10","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2025\/05\/28\/lactate-trains-immunity-alba-llibre\/"},"modified":"2025-05-28T06:47:10","modified_gmt":"2025-05-28T04:47:10","slug":"lactate-trains-immunity-alba-llibre","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2025\/05\/28\/lactate-trains-immunity-alba-llibre\/","title":{"rendered":"Lactate trains immunity. Alba Llibre"},"content":{"rendered":"<div>\n<p><b>Trends Immunol<\/b>. 2025 May 26:S1471-4906(25)00123-1. doi: 10.1016\/j.it.2025.05.002. Online ahead of print.<\/p>\n<p><b>ABSTRACT<\/b><\/p>\n<p>Understanding the mechanisms implicated in the establishment of trained immunity could aid the design of novel therapeutic approaches. By studying Bacille Calmette-Guerin (BCG) vaccination in a human cohort, Ziogas and colleagues demonstrate the role of lactate generation and its use for histone lactylation as a key mechanism for establishing innate immune memory.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40425374\/?utm_source=WordPress&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20250528004701&amp;v=2.18.0.post9+e462414\">40425374<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2025.05.002\">10.1016\/j.it.2025.05.002<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2025 May 26:S1471-4906(25)00123-1. doi: 10.1016\/j.it.2025.05.002. Online ahead of print. ABSTRACT Understanding the mechanisms implicated in the establishment of trained immunity could aid the design of novel therapeutic approaches. By studying Bacille Calmette-Guerin (BCG) vaccination in a human cohort, Ziogas and colleagues demonstrate the role of lactate generation and its use for histone lactylation &#8230; <a title=\"Lactate trains immunity. Alba Llibre\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2025\/05\/28\/lactate-trains-immunity-alba-llibre\/\" aria-label=\"Read more about Lactate trains immunity. Alba Llibre\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-33552","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/33552","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=33552"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/33552\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=33552"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=33552"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=33552"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}