{"id":39340,"date":"2025-07-31T06:47:30","date_gmt":"2025-07-31T04:47:30","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2025\/07\/31\/targeting-wstf-degradation-to-resolve-chronic-inflammation-weiqiong-feng\/"},"modified":"2025-07-31T06:47:30","modified_gmt":"2025-07-31T04:47:30","slug":"targeting-wstf-degradation-to-resolve-chronic-inflammation-weiqiong-feng","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2025\/07\/31\/targeting-wstf-degradation-to-resolve-chronic-inflammation-weiqiong-feng\/","title":{"rendered":"Targeting WSTF degradation to resolve chronic inflammation. Weiqiong Feng"},"content":{"rendered":"<div>\n<p><b>Trends Immunol<\/b>. 2025 Jul 29:S1471-4906(25)00176-0. doi: 10.1016\/j.it.2025.07.009. Online ahead of print.<\/p>\n<p><b>ABSTRACT<\/b><\/p>\n<p>Chronic inflammation drives diseases like osteoarthritis and MASH, yet its molecular distinction from acute inflammation remains unclear. In a recent Nature study, Wang et al. revealed that chronic stress triggers WSTF degradation via nuclear autophagy, amplifying NF-\u03baB responses. Blocking this pathway attenuates chronic inflammation while sparing acute immunity.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40738769\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20250731004728&amp;v=2.18.0.post9+e462414\">40738769<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2025.07.009\">10.1016\/j.it.2025.07.009<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2025 Jul 29:S1471-4906(25)00176-0. doi: 10.1016\/j.it.2025.07.009. Online ahead of print. ABSTRACT Chronic inflammation drives diseases like osteoarthritis and MASH, yet its molecular distinction from acute inflammation remains unclear. In a recent Nature study, Wang et al. revealed that chronic stress triggers WSTF degradation via nuclear autophagy, amplifying NF-\u03baB responses. Blocking this pathway attenuates chronic &#8230; <a title=\"Targeting WSTF degradation to resolve chronic inflammation. Weiqiong Feng\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2025\/07\/31\/targeting-wstf-degradation-to-resolve-chronic-inflammation-weiqiong-feng\/\" aria-label=\"Read more about Targeting WSTF degradation to resolve chronic inflammation. Weiqiong Feng\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-39340","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/39340","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=39340"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/39340\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=39340"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=39340"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=39340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}