{"id":39985,"date":"2025-08-09T19:47:37","date_gmt":"2025-08-09T17:47:37","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2025\/08\/09\/inosine-boosts-infant-antiviral-immunity-ziad-al-nabhani\/"},"modified":"2025-08-09T19:47:37","modified_gmt":"2025-08-09T17:47:37","slug":"inosine-boosts-infant-antiviral-immunity-ziad-al-nabhani","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2025\/08\/09\/inosine-boosts-infant-antiviral-immunity-ziad-al-nabhani\/","title":{"rendered":"Inosine boosts infant antiviral immunity. Ziad Al Nabhani"},"content":{"rendered":"<div>\n<p><b>Trends Immunol<\/b>. 2025 Aug 7:S1471-4906(25)00180-2. doi: 10.1016\/j.it.2025.07.013. Online ahead of print.<\/p>\n<p><b>ABSTRACT<\/b><\/p>\n<p>Early antibiotic exposure disrupts the gut microbiota, impairing newborn antiviral immunity. Stevens et al. uncover that inosine, a metabolite produced by gut bacteria, restores the function of antiviral T cells by modulating gene regulation, boosting lung immune defenses against respiratory viruses.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40781010\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20250809134734&amp;v=2.18.0.post9+e462414\">40781010<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2025.07.013\">10.1016\/j.it.2025.07.013<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2025 Aug 7:S1471-4906(25)00180-2. doi: 10.1016\/j.it.2025.07.013. Online ahead of print. ABSTRACT Early antibiotic exposure disrupts the gut microbiota, impairing newborn antiviral immunity. Stevens et al. uncover that inosine, a metabolite produced by gut bacteria, restores the function of antiviral T cells by modulating gene regulation, boosting lung immune defenses against respiratory viruses. PMID:40781010 | &#8230; <a title=\"Inosine boosts infant antiviral immunity. Ziad Al Nabhani\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2025\/08\/09\/inosine-boosts-infant-antiviral-immunity-ziad-al-nabhani\/\" aria-label=\"Read more about Inosine boosts infant antiviral immunity. Ziad Al Nabhani\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-39985","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/39985","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=39985"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/39985\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=39985"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=39985"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=39985"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}