{"id":41646,"date":"2025-08-28T06:48:51","date_gmt":"2025-08-28T04:48:51","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2025\/08\/28\/gut-microbiota-specific-t-cell-subset-drives-cns-inflammation-bingjun-ha\/"},"modified":"2025-08-28T06:48:51","modified_gmt":"2025-08-28T04:48:51","slug":"gut-microbiota-specific-t-cell-subset-drives-cns-inflammation-bingjun-ha","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2025\/08\/28\/gut-microbiota-specific-t-cell-subset-drives-cns-inflammation-bingjun-ha\/","title":{"rendered":"Gut microbiota-specific T cell subset drives CNS inflammation. Bingjun Ha"},"content":{"rendered":"<div>\n<p><b>Trends Immunol<\/b>. 2025 Aug 26:S1471-4906(25)00200-5. doi: 10.1016\/j.it.2025.08.002. Online ahead of print.<\/p>\n<p><b>ABSTRACT<\/b><\/p>\n<p>Gut dysbiosis and intestinal inflammation may contribute to neurological disorders through the gut-brain axis. A recent report by White et al. uncovered that intestinal inflammation triggers the migration of microbiota-specific CD4<sup>+<\/sup> T cells to the brain, where they drive neuroinflammatory responses via IL-23R\/GM-CSF.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40866136\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20250828004848&amp;v=2.18.0.post9+e462414\">40866136<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2025.08.002\">10.1016\/j.it.2025.08.002<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2025 Aug 26:S1471-4906(25)00200-5. doi: 10.1016\/j.it.2025.08.002. Online ahead of print. ABSTRACT Gut dysbiosis and intestinal inflammation may contribute to neurological disorders through the gut-brain axis. A recent report by White et al. uncovered that intestinal inflammation triggers the migration of microbiota-specific CD4+ T cells to the brain, where they drive neuroinflammatory responses via IL-23R\/GM-CSF. &#8230; <a title=\"Gut microbiota-specific T cell subset drives CNS inflammation. Bingjun Ha\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2025\/08\/28\/gut-microbiota-specific-t-cell-subset-drives-cns-inflammation-bingjun-ha\/\" aria-label=\"Read more about Gut microbiota-specific T cell subset drives CNS inflammation. Bingjun Ha\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-41646","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/41646","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=41646"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/41646\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=41646"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=41646"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=41646"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}