{"id":46510,"date":"2025-10-23T06:50:11","date_gmt":"2025-10-23T04:50:11","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2025\/10\/23\/dual-effects-and-balanced-regulation-of-cytokines-in-sepsis-changli-wang\/"},"modified":"2025-10-23T06:50:11","modified_gmt":"2025-10-23T04:50:11","slug":"dual-effects-and-balanced-regulation-of-cytokines-in-sepsis-changli-wang","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2025\/10\/23\/dual-effects-and-balanced-regulation-of-cytokines-in-sepsis-changli-wang\/","title":{"rendered":"Dual effects and balanced regulation of cytokines in sepsis. Changli Wang"},"content":{"rendered":"<div>\n<p><b>Trends Immunol<\/b>. 2025 Oct 21:S1471-4906(25)00246-7. doi: 10.1016\/j.it.2025.10.002. Online ahead of print.<\/p>\n<p><b>ABSTRACT<\/b><\/p>\n<p>Sepsis, a life-threatening condition triggered by infection, disrupts the body&#8217;s immune balance and remains a major global health challenge. This forum explores the dual roles of cytokines in sepsis: their overactivation drives &#8216;cytokine storms,&#8217; and dysregulation leads to immunosuppression. It also discusses regulatory mechanisms for developing targeted therapies.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41125507\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20251023005011&amp;v=2.18.0.post22+67771e2\">41125507<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2025.10.002\">10.1016\/j.it.2025.10.002<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2025 Oct 21:S1471-4906(25)00246-7. doi: 10.1016\/j.it.2025.10.002. Online ahead of print. ABSTRACT Sepsis, a life-threatening condition triggered by infection, disrupts the body&#8217;s immune balance and remains a major global health challenge. This forum explores the dual roles of cytokines in sepsis: their overactivation drives &#8216;cytokine storms,&#8217; and dysregulation leads to immunosuppression. It also discusses regulatory &#8230; <a title=\"Dual effects and balanced regulation of cytokines in sepsis. Changli Wang\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2025\/10\/23\/dual-effects-and-balanced-regulation-of-cytokines-in-sepsis-changli-wang\/\" aria-label=\"Read more about Dual effects and balanced regulation of cytokines in sepsis. Changli Wang\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-46510","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/46510","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=46510"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/46510\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=46510"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=46510"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=46510"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}