{"id":51544,"date":"2025-12-19T09:36:13","date_gmt":"2025-12-19T08:36:13","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2025\/12\/19\/ultrasensitive-test-systems-are-required-to-quantify-interferon-alpha-protein-in-serum-samples-valueliis-haljasmagi-sandra-meisalu-vincent-bondet-part-peterson-darragh-duffy-kai-k\/"},"modified":"2025-12-19T09:36:13","modified_gmt":"2025-12-19T08:36:13","slug":"ultrasensitive-test-systems-are-required-to-quantify-interferon-alpha-protein-in-serum-samples-valueliis-haljasmagi-sandra-meisalu-vincent-bondet-part-peterson-darragh-duffy-kai-k","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2025\/12\/19\/ultrasensitive-test-systems-are-required-to-quantify-interferon-alpha-protein-in-serum-samples-valueliis-haljasmagi-sandra-meisalu-vincent-bondet-part-peterson-darragh-duffy-kai-k\/","title":{"rendered":"Ultrasensitive Test Systems Are Required to Quantify Interferon Alpha Protein in Serum Samples. [[{&#8220;value&#8221;:&#8221;Liis Haljasm\u00e4gi, \nSandra Meisalu, \nVincent Bondet, \nP\u00e4rt Peterson, \nDarragh Duffy, \nKai Kisand&#8221;}]]"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/onlinelibrary.wiley.com\/cms\/asset\/01d3792b-8ba7-4cfb-af81-205a97bf0b36\/eji70100-gra-0001-m.png\" alt=\"Ultrasensitive Test Systems Are Required to Quantify Interferon Alpha Protein in Serum Samples\" \/><\/p>\n<p>Selecting a sensitive test system is crucial to measure IFN\u03b1 in serum samples. Simoa digital ELISA stands out for its high sensitivity and strong correlation with transcript-based IFN-induced gene (ISG) scores. In SLE, the ISG score is explained by circulating IFN\u03b1 levels with negligible contribution from IFN\u03b2 or IFN\u03b3. Created in BioRender.<\/p>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Selecting a sensitive test system is crucial to measure IFN\u03b1 in serum samples. Simoa digital ELISA stands out for its high sensitivity and strong correlation with transcript-based IFN-induced gene (ISG) scores. In SLE, the ISG score is explained by circulating IFN\u03b1 levels with negligible contribution from IFN\u03b2 or IFN\u03b3. Created in BioRender.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[112,42],"tags":[],"class_list":["post-51544","post","type-post","status-publish","format-standard","hentry","category-european-journal-of-immunology","category-publicaciones"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/51544","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=51544"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/51544\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=51544"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=51544"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=51544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}