{"id":52562,"date":"2026-01-10T06:39:05","date_gmt":"2026-01-10T05:39:05","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2026\/01\/10\/emerging-diagnostic-techniques-in-sarcoidosis-a-path-forward\/"},"modified":"2026-01-10T06:39:05","modified_gmt":"2026-01-10T05:39:05","slug":"emerging-diagnostic-techniques-in-sarcoidosis-a-path-forward","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2026\/01\/10\/emerging-diagnostic-techniques-in-sarcoidosis-a-path-forward\/","title":{"rendered":"Emerging diagnostic techniques in sarcoidosis: a path forward"},"content":{"rendered":"<div>\n<p><b>Curr Opin Immunol<\/b>. 2026 Jan 8;99:102716. doi: 10.1016\/j.coi.2025.102716. Online ahead of print.<\/p>\n<p><b>ABSTRACT<\/b><\/p>\n<p>Sarcoidosis is a complex and heterogenous disease of which the diagnosis is based on clinical and radiological findings, histopathology showing non-caseating granulomas, and exclusion of other granulomatous diseases. Several tools are well established in the diagnostic pathway, such as pulmonary function tests, broncho-alveolar lavage, endobronchial ultrasound-guided transbronchial needle aspiration, transbronchial and endobronchial biopsies, the serum biomarkers serum angiotensin converting enzyme and soluble interleukin-2 receptor, and imaging, mainly chest computed tomography (CT), 18-fluorodeoxyglucose-positron emission tomography\/CT, and brain and cardiac magnetic resonance imaging. However, continuous efforts in the field have been made, and a variety of novel methods are arising. These might be less invasive, can lead to a more secure diagnosis, promote risk stratification, or guide treatment decisions, especially when combined in a stepwise multimodal approach. In this work, we aim to give an overview of the current diagnostic standards in sarcoidosis and discuss the new kids on the block.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41512550\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_content=8900118&amp;ff=20260110003905&amp;v=2.18.0.post22+67771e2\">41512550<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.coi.2025.102716\">10.1016\/j.coi.2025.102716<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Curr Opin Immunol. 2026 Jan 8;99:102716. doi: 10.1016\/j.coi.2025.102716. Online ahead of print. ABSTRACT Sarcoidosis is a complex and heterogenous disease of which the diagnosis is based on clinical and radiological findings, histopathology showing non-caseating granulomas, and exclusion of other granulomatous diseases. Several tools are well established in the diagnostic pathway, such as pulmonary function tests, &#8230; <a title=\"Emerging diagnostic techniques in sarcoidosis: a path forward\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2026\/01\/10\/emerging-diagnostic-techniques-in-sarcoidosis-a-path-forward\/\" aria-label=\"Read more about Emerging diagnostic techniques in sarcoidosis: a path forward\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59,42],"tags":[],"class_list":["post-52562","post","type-post","status-publish","format-standard","hentry","category-current-opinion-in-immunology","category-publicaciones"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/52562","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=52562"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/52562\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=52562"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=52562"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=52562"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}