{"id":55295,"date":"2026-02-08T06:35:45","date_gmt":"2026-02-08T05:35:45","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2026\/02\/08\/flt3l-from-interfollicular-stroma-maintains-resident-dendritic-cells-arpa-aintablian\/"},"modified":"2026-02-08T06:35:45","modified_gmt":"2026-02-08T05:35:45","slug":"flt3l-from-interfollicular-stroma-maintains-resident-dendritic-cells-arpa-aintablian","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2026\/02\/08\/flt3l-from-interfollicular-stroma-maintains-resident-dendritic-cells-arpa-aintablian\/","title":{"rendered":"Flt3L from interfollicular stroma maintains resident dendritic cells. Arpa Aintablian"},"content":{"rendered":"<div>\n<p><b>Trends Immunol<\/b>. 2026 Feb 6:S1471-4906(26)00013-X. doi: 10.1016\/j.it.2026.01.010. Online ahead of print.<\/p>\n<p><b>ABSTRACT<\/b><\/p>\n<p>Dendritic cell (DC) maintenance and positioning are essential for their function in lymph nodes. Wu et al. identify gremlin1 (Grem1)<sup>+<\/sup> fibroblastic reticular cells as critical source of niche-specific Fms-like tyrosine kinase 3 ligand (Flt3L) for conventional DC maintenance in health and disease, highlighting stromal cells as key regulators of immunity.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41654480\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20260208003540&amp;v=2.18.0.post22+67771e2\">41654480<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2026.01.010\">10.1016\/j.it.2026.01.010<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2026 Feb 6:S1471-4906(26)00013-X. doi: 10.1016\/j.it.2026.01.010. Online ahead of print. ABSTRACT Dendritic cell (DC) maintenance and positioning are essential for their function in lymph nodes. Wu et al. identify gremlin1 (Grem1)+ fibroblastic reticular cells as critical source of niche-specific Fms-like tyrosine kinase 3 ligand (Flt3L) for conventional DC maintenance in health and disease, highlighting &#8230; <a title=\"Flt3L from interfollicular stroma maintains resident dendritic cells. Arpa Aintablian\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2026\/02\/08\/flt3l-from-interfollicular-stroma-maintains-resident-dendritic-cells-arpa-aintablian\/\" aria-label=\"Read more about Flt3L from interfollicular stroma maintains resident dendritic cells. Arpa Aintablian\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-55295","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/55295","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=55295"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/55295\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=55295"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=55295"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=55295"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}