{"id":63162,"date":"2026-05-02T06:53:43","date_gmt":"2026-05-02T04:53:43","guid":{"rendered":"https:\/\/inmuno.es\/index.php\/2026\/05\/02\/scaling-immunity-sickness-as-a-host-defense-strategy-a-clare-sparling\/"},"modified":"2026-05-02T06:53:43","modified_gmt":"2026-05-02T04:53:43","slug":"scaling-immunity-sickness-as-a-host-defense-strategy-a-clare-sparling","status":"publish","type":"post","link":"https:\/\/inmuno.es\/index.php\/2026\/05\/02\/scaling-immunity-sickness-as-a-host-defense-strategy-a-clare-sparling\/","title":{"rendered":"Scaling immunity: sickness as a host defense strategy. A Clare Sparling"},"content":{"rendered":"<div>\n<p><b>Trends Immunol<\/b>. 2026 Apr 30:S1471-4906(26)00076-1. doi: 10.1016\/j.it.2026.03.015. Online ahead of print.<\/p>\n<p><b>ABSTRACT<\/b><\/p>\n<p>Sickness, or sickness behavior, is a state of altered physiology and behavior generated by the brain-immune axis during infection, which is generally assumed to contribute to host defense. Here, we examine this assumption by framing sickness as organismal-scale immunity and explore predicted parallels with immunity at the cellular and tissue scales.<\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42067422\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_content=100966032&amp;ff=20260502005343&amp;v=2.19.0.post6+133c1fe\">42067422<\/a> | DOI:<a href=\"https:\/\/doi.org\/10.1016\/j.it.2026.03.015\">10.1016\/j.it.2026.03.015<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Trends Immunol. 2026 Apr 30:S1471-4906(26)00076-1. doi: 10.1016\/j.it.2026.03.015. Online ahead of print. ABSTRACT Sickness, or sickness behavior, is a state of altered physiology and behavior generated by the brain-immune axis during infection, which is generally assumed to contribute to host defense. Here, we examine this assumption by framing sickness as organismal-scale immunity and explore predicted parallels &#8230; <a title=\"Scaling immunity: sickness as a host defense strategy. A Clare Sparling\" class=\"read-more\" href=\"https:\/\/inmuno.es\/index.php\/2026\/05\/02\/scaling-immunity-sickness-as-a-host-defense-strategy-a-clare-sparling\/\" aria-label=\"Read more about Scaling immunity: sickness as a host defense strategy. A Clare Sparling\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42,68],"tags":[],"class_list":["post-63162","post","type-post","status-publish","format-standard","hentry","category-publicaciones","category-trends-in-immunology"],"_links":{"self":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/63162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/comments?post=63162"}],"version-history":[{"count":0,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/posts\/63162\/revisions"}],"wp:attachment":[{"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/media?parent=63162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/categories?post=63162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inmuno.es\/index.php\/wp-json\/wp\/v2\/tags?post=63162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}