- Glycome remodeling programs pathogenic γδ T17 cell responses in autoimmunity
Science Immunology, Volume 11, Issue 124, October 2026.
- STAT3 operates as an inflammation-dependent transcriptional switch in antiviral NK cells
Science Immunology, Volume 11, Issue 124, October 2026.
- The IKK complex and TBK1/IKKε are recruited to STING through distinct mechanisms to activate NF-κB signaling
Science Immunology, Volume 11, Issue 124, October 2026.
- Follicle-associated epithelial tuft cells amplify type 2 mucosal immunity and IgA production
Science Immunology, Volume 11, Issue 124, October 2026.
- B1-like innate B cells are present in adult human organs in homeostasis
Science Immunology, Volume 11, Issue 124, October 2026.
- Pairing up to decode recognition
by Jonathan S. Maltzmannnn
Science Immunology, Volume 11, Issue 124, October 2026.
- Migratory dermal γδ T cells determine the balance between lung immunity and tissue damage during helminth infection
Science Immunology, Volume 11, Issue 124, October 2026.
- Old dog, new tricks: Astrocytes use the CD40 pathway to propagate neuroinflammation
by Jennifer L. Gommerman
Science Immunology, Volume 11, Issue 124, October 2026.
- Multiomic analysis of malignant ascites defines RORC-expressing dendritic cells at sites of metastasis
Science Immunology, Volume 11, Issue 124, October 2026.
- Specific targeting of MR1-antigen complexes using nanobodies
Science Immunology, Volume 11, Issue 123, September 2026.
- Fibrinoid-associated neutrophils promote invasive placentation and neutrophil reprogramming at the maternal-fetal interface
Science Immunology, Volume 11, Issue 123, September 2026.
- In vitro induction of human germinal center B cells
by David G. Priest, Melike Fusun Demir, Wataru Ise, James B. Wing
Science Immunology, Volume 11, Issue 123, September 2026.
- Erratum for the Review “Regulation of inflammation by oxidized lipids”
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 123, September 2026.
- In vivo CRISPR screens identify the glutamine transporter SLC1A5 as a metabolic barrier to antitumor immunity
Science Immunology, Volume 11, Issue 123, September 2026.
- AMnESTI reverses age-associated lung immune decline to drive heterosubtypic protection by inactivated influenza vaccines
Science Immunology, Volume 11, Issue 123, September 2026.
- The many roads to B cell memory
by Oluwagbemiga A. Ojo and Stephanie C. Eisenbarth
Science Immunology, Volume 11, Issue 123, September 2026.
- Old dog with new tricks: SARS-CoV-2 variant–specific B cells complement imprinted memory
by Lauren B. Rodda
Science Immunology, Volume 11, Issue 123, September 2026.
- Tissue mitochondrial activity dictates the macrophage pool size
Science Immunology, Volume 11, Issue 123, September 2026.
- Positive selection of IgG over IgM plasma cells through BCR isotype–specific antigen presentation and signaling
Science Immunology, Volume 11, Issue 123, September 2026.
- Adaptive motility enables neutrophils to rapidly navigate confined capillaries
Science Immunology, Volume 11, Issue 123, September 2026.
- Platelet-derived serotonin drives age-related lung pathology in SARS-CoV-2 infection
Science Immunology, Volume 11, Issue 122, August 2026.
- Type I IFN–induced IFN-γ instructs monocyte-mediated systemic bacterial protection during type 2 intestinal helminth infection
Science Immunology, Volume 11, Issue 122, August 2026.
- Androgen signaling via sympathetic neurons regulates allergic pulmonary inflammation
by Xiaofan Tu, Hongjie Chen, Xiaoran Ma, Chantal Donovan, Jing Yang
Science Immunology, Volume 11, Issue 122, August 2026.
- CAR T cell–derived TNF is an early determinant of cytokine release syndrome severity
Science Immunology, Volume 11, Issue 122, August 2026.
- Fusion of IgG antibodies to albumin inhibits transport across the placenta
Science Immunology, Volume 11, Issue 122, August 2026.
- Regulation of inflammation by oxidized lipids
by Marco Di Gioia and Ivan Zanoni
Science Immunology, Volume 11, Issue 122, August 2026.
- A dendritic cell autophagy–neutrophil axis limits intratumoral STING immunotherapy
Science Immunology, Volume 11, Issue 122, August 2026.
- Mist-ical memory: The airway defenses induced by FluMist vaccination in adults
by Huzaifa Zohair and Priyadharshini Devarajan
Science Immunology, Volume 11, Issue 122, August 2026.
- PKM2 works “off the books” to drive effector T cell function in MS
by Alexia Falle and Manu Rangachari
Science Immunology, Volume 11, Issue 122, August 2026.
- Misfirin’ pyrin
by Fiachra Humphries
Science Immunology, Volume 11, Issue 122, August 2026.
- A genotype-first approach reveals the molecular basis of pyrin inflammasome activation
Science Immunology, Volume 11, Issue 122, August 2026.
- An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation
Science Immunology, Volume 11, Issue 122, August 2026.
- An autoinflammatory CDC42 variant M45L demonstrates the mechanism of pyrin inflammasome activation
Science Immunology, Volume 11, Issue 122, August 2026.
- Two differentiation pathways generate large peritoneal macrophages with one replenishing mesothelial border macrophages
Science Immunology, Volume 11, Issue 121, July 2026.
- Dynamic expression of IL-21 in effector CD8 T cells helps control chronic infections
Science Immunology, Volume 11, Issue 121, July 2026.
- Genomic correlates of clinical CAR T cell activity
Science Immunology, Volume 11, Issue 121, July 2026.
- Dynamic regulation of lysine and arginine metabolism promotes immune evasion by limiting T cell function in cancer
Science Immunology, Volume 11, Issue 121, July 2026.
- Macrophage-derived oxysterols organize T helper 2 cells to suppress type 1 inflammation during pulmonary fungal infection
Science Immunology, Volume 11, Issue 121, July 2026.
- Mucosal tissue cues shape B cell memory through the IgA BCR
Science Immunology, Volume 11, Issue 121, July 2026.
- Sp1 links CD46 to CD4 T cell metabolic fitness, survival, and retroviral control
Science Immunology, Volume 11, Issue 121, July 2026.
- The efficacy of immunotherapy in glioma requires distal B cell responses in tumor-draining lymph nodes
Science Immunology, Volume 11, Issue 121, July 2026.
- A breath of fresh AIR in novel CAR T cell design
by Bin-Bin Schell and Laura Solt
Science Immunology, Volume 11, Issue 121, July 2026.
- Celebrating a decade of progress at Science Immunology
by Seth Thomas Scanlon
Science Immunology, Volume 11, Issue 121, July 2026.
- ILC2s shoot 4 making 13s
by Sophia Villa and Shiv Pillai
Science Immunology, Volume 11, Issue 121, July 2026.
- The evolving biology of T cell memory: A dynamic continuum of function and persistence
by Stephen J. Turner, Daniel Thiele, Nicole L. La Gruta
Science Immunology, Volume 11, Issue 121, July 2026.
- Molecular and tissue regulation of memory B cells
by Mauro Gaya and Kim L. Good-Jacobson
Science Immunology, Volume 11, Issue 121, July 2026.
- Evolution and development of innate immune memory
by Maziar Divangahi and Eva Kaufmann
Science Immunology, Volume 11, Issue 121, July 2026.
- Memories that endure
by Leoma Bere, Christiana Fogg, Hannah Isles, Claire Olingy, Seth Thomas Scanlon
Science Immunology, Volume 11, Issue 121, July 2026.
- Treg cells promote immunotherapy-induced immune evasion by restraining CD4 T cell control of MHC-I–deficient metastatic pancreatic cancer
Science Immunology, Volume 11, Issue 120, June 2026.
- Erratum for the Research Article “Claudins interact with LILRB immune inhibitory receptors to promote myeloid immunosuppression in cancer”
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 120, June 2026.
- Langerhans cell control of early-life dermal lymphatic development shapes adult immunity
Science Immunology, Volume 11, Issue 120, June 2026.
- Bacterial infection reshapes monocyte and macrophage ontogeny at the CNS borders
Science Immunology, Volume 11, Issue 120, June 2026.
- Bioactive enhanced adjuvant chemokine oligonucleotide nanoparticles (BEACONs) for mucosal vaccination against genital herpes
Science Immunology, Volume 11, Issue 120, June 2026.
- CXCL16-mediated recruitment of γδ T cells to the brain reduces sociability in mice
Science Immunology, Volume 11, Issue 120, June 2026.
- DDX6 induces immunosuppression in cancer by disrupting structural stability of endogenous double-stranded RNAs
Science Immunology, Volume 11, Issue 120, June 2026.
- The tissue-specific regulation of immunobiology by IL-17 signaling
by Yang Li, Shachi P. Vyas, Peter Draber, Rami Bechara, Sarah L. Gaffen
Science Immunology, Volume 11, Issue 120, June 2026.
- Rogue clones: When MS autoimmunity goes viral
by Jan D. Lünemann
Science Immunology, Volume 11, Issue 120, June 2026.
- Let your light shine down
by Jada M. Coffey and Gabriel K. Griffin
Science Immunology, Volume 11, Issue 120, June 2026.
- Cytotoxic CD39+ tumor-associated NK cells respond to NKG2A blockade in lung cancer
Science Immunology, Volume 11, Issue 120, June 2026.
- Efferocytosis induces proangiogenic function and chromatin remodeling in tumor-associated macrophages
Science Immunology, Volume 11, Issue 120, June 2026.
- Atlas of human gut-associated lymphoid tissue reveals immunomodulatory interactions of B cells
Science Immunology, Volume 11, Issue 120, June 2026.
- Transcriptional and chromatin dynamics in macrophage differentiation and activation
Science Immunology, Volume 11, Issue 119, May 2026.
- Mitochondrial complex I activity promotes antigen cross-presentation in dendritic cells
Science Immunology, Volume 11, Issue 119, May 2026.
- Gastrointestinal tuft cells: Recent insights and next questions
by Thornton W. Thompson and Jakob von Moltke
Science Immunology, Volume 11, Issue 119, May 2026.
- PD-1 signaling and PD-1 blockade–mediated tumor control are established at microvillar T cell contacts
Science Immunology, Volume 11, Issue 119, May 2026.
- Goblet cells tune ILC2 activity through a gut-specific response checkpoint
Science Immunology, Volume 11, Issue 119, May 2026.
- Erratum for the Research Article “Single-cell profiling reveals diverse γδ T cell subsets in ulcerative colitis”
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 119, May 2026.
- In vivo reprogramming of cytotoxic effector CD8 T cells via fractalkine-conjugated mRNA-LNPs
Science Immunology, Volume 11, Issue 119, May 2026.
- Monocyte-derived macrophages drive neurological tissue damage through mitochondrial reactive oxygen species
Science Immunology, Volume 11, Issue 119, May 2026.
- Foxp3: The epigenetic engineer of regulatory T cell identity
by Mieke Metzemaekers and Ralph Stadhouders
Science Immunology, Volume 11, Issue 119, May 2026.
- Citraconate preserves T cell stemness and antitumor immunity
Science Immunology, Volume 11, Issue 119, May 2026.
- B cells gone broad: A deep dive into SARS-CoV-2 antibody breadth
by Easton E. Ford and Melissa L. Smith
Science Immunology, Volume 11, Issue 119, May 2026.
- A parasite partner for regulatory affairs
by Isabella O. Conway and Christopher A. Hunter
Science Immunology, Volume 11, Issue 119, May 2026.
- Foxp3 drives context-dependent epigenetic programs that define regulatory T cell molecular identity and function
Science Immunology, Volume 11, Issue 119, May 2026.
- An adaptive cellular source of IL-17A and IL-17F is critical for the induction of experimental autoimmune encephalomyelitis
Science Immunology, Volume 11, Issue 118, April 2026.
- Erratum for the Research Article “The chemerin-CMKLR1 axis limits thermogenesis by controlling a beige adipocyte/IL-33/type 2 innate immunity circuit”
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 118, April 2026.
- Mitochondrial fission mediates an evolutionarily conserved antibacterial defense response
Science Immunology, Volume 11, Issue 118, April 2026.
- Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense
Science Immunology, Volume 11, Issue 118, April 2026.
- The autoantigen TRIM21 assembles proinflammatory immune complexes after lytic cell death
Science Immunology, Volume 11, Issue 118, April 2026.
- Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge
Science Immunology, Volume 11, Issue 118, April 2026.
- The rise of spatial TCR profiling: Emerging technologies and open challenges
by Yinglu Tang and Tao Wang
Science Immunology, Volume 11, Issue 118, April 2026.
- Erratum for the Research Article “A noncanonical cytoplasmic role for BUB1 in restraining DNA damage–induced dsRNA accumulation and sensing within stress granules”
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 118, April 2026.
- Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer
Science Immunology, Volume 11, Issue 118, April 2026.
- Intratumoral Treg cell ablation elicits NK cell–mediated control of CD8 T cell–resistant tumors
Science Immunology, Volume 11, Issue 118, April 2026.
- Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF
Science Immunology, Volume 11, Issue 118, April 2026.
- Copper supports regulatory T cell energetic state to sustain peripheral immune tolerance
Science Immunology, Volume 11, Issue 118, April 2026.
- Claudins interact with LILRB immune inhibitory receptors to promote myeloid immunosuppression in cancer
Science Immunology, Volume 11, Issue 118, April 2026.
- The epitope tax: Antibody feedback and the economics of germinal center competition
by Wallace P. Bezerra and Adam Williams
Science Immunology, Volume 11, Issue 118, April 2026.
- Skull-pting meningeal immunity: Skull bone channels shape neonatal meningeal immune cell trafficking
by Emma N. Barnes and David R. Martinez
Science Immunology, Volume 11, Issue 118, April 2026.
- Intestinal epithelial MHC class II induces encephalitogenic CD4 T cells and initiates central nervous system autoimmunity
Science Immunology, Volume 11, Issue 117, March 2026.
- Palmitate-induced mitochondrial damage restricts histone acetylation in CD8 T cells to impair antitumor immunity
Science Immunology, Volume 11, Issue 117, March 2026.
- Erratum for the Research Article “TCRγ constant usage tunes human γδ T cell antigen sensitivity, thymic programming, and peripheral function”
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 117, March 2026.
- Macrophages restrict tumor immune infiltration by controlling collagen topography
Science Immunology, Volume 11, Issue 117, March 2026.
- Immune mechanisms of congenital Zika syndrome
by Abhay P. S. Rathore and Ashley L. St. John
Science Immunology, Volume 11, Issue 117, March 2026.
- The B cell receptor–mTOR signaling axis restricts the accumulation of lung tissue–resident memory B cells after influenza infection
Science Immunology, Volume 11, Issue 117, March 2026.
- T cell development from expanded hematopoietic progenitors reveals initiation control by Lmo2 and Flt3L priming
Science Immunology, Volume 11, Issue 117, March 2026.
- Inflammatory ILC2s migrate to distal tissues during infection using stage-specific S1P receptors
Science Immunology, Volume 11, Issue 117, March 2026.
- EBV grants B cells a license for immortality in the CNS
by Yoshiaki Yasumizu
Science Immunology, Volume 11, Issue 117, March 2026.
- Identification and characterization of dietary antigens in oral tolerance
Science Immunology, Volume 11, Issue 117, March 2026.
- IgG4 on the dance floor: Partners swapped by Fab-arm exchange
by Ailis Grieshaber and Kevin C. O’Connor
Science Immunology, Volume 11, Issue 117, March 2026.
