NOTICIAS
- Researchers identify key pathway that drives T-cell exhaustion in cancer immunotherapy
- Early nicotine exposure alters immune development and worsens later flu infections in mice
- Cancer-promoting protein also helps engineered immune cells fight tumors in lab tests
- Reversible genetic switches could give cancer immunotherapy more precise control
- How food allergy risk changes as children grow
- Immune system discoveries reveal how body balances defense, protection and repair
- Why autoantibodies may be linked to preterm birth risk in some women
- Abnormal antibodies that disrupt DNA repair could explain childhood cancer
- Enhanced CAR T-cell therapy shows early promise for B-cell cancers in first-in-human trial
- Scientists identify clues to making immunotherapy more effective against glioblastoma
- Alcohol and the brain interact through immune cells, new research shows
- Human stem-cell model reveals a shared origin for tissue-resident macrophages
- Prime editing repairs immune disorder defect in patient’s own blood stem cells
- Kidney biopsy maps reveal immune clusters that may keep inflammation going
- Protein reins in intestinal inflammation by curbing an overactive immune signal
- Tumor suppressor gene mutations trigger immune activation in early oral cancer
PUBLICACIONES
- Researchers identify key pathway that drives T-cell exhaustion in cancer immunotherapy
- Early nicotine exposure alters immune development and worsens later flu infections in mice
- Transient manganese exposure reprograms bone marrow-derived macrophages toward a stable anti-inflammatory memory state
- TNFα promotes brain-predominant EAE independent of IFNγ and IL-17A in HLA-DR3 transgenic mice
- Selective expansion of neoantigen-specific peripheral blood lymphocytes through antigen-presenting cell-T cell conjugate isolation
- Temporal and therapeutic confounders in predicting efficacy of immunotherapy rechallenge via baseline intratumoral tertiary lymphoid structures
- Distinct genomic landscapes of mismatch-repair deficiency (dMMR)/microsatellite instability-high (MSI-H) gastrointestinal (GI) cancer depending on tumor mutation burden (TMB) levels
- Inducible cAMP Early Repressor Limits Glycolytic Programming in Regulatory T Cells and Supports Control of Inflammatory Colitis. [[{“value”:”Aleksandra Lopez Krol, Luana Silva, Daniele C. Nascimento, Sophie M. Oberwalder, Hitikk Chawla, Gabriel Alberto Barbosa de Carvalho, Fatima Boukhallouk, Monica Romero, Anne Hausen, Matthias M. Gaida, Luciana Berod, José Carlos Alves‐Filho, Tim Sparwasser”}]]
- Discovery of Avian TCRVβ2+ T Cells Recognizing the Endogenous Ganglioside via a chCD1.1‐Dependent Pathway. [[{“value”:”Nitin Kamble, Faisal R Anjum, Shahriar Behboudi”}]]
- Defense and subversion: multilevel mitochondrial quality control and pathway‑specific mitophagy outcomes in Mycobacterium tuberculosis infection
- Correction: Postbiotic Enterococcus faecalis EF-2001 induces IL-10 production through macrophage scavenger receptor 1-mediated phagocytosis
- Glaucoma neurodegeneration: targeted modulation of intraocular immune pathways – a review of novel therapeutic advances
- Research progress of mitophagy and its targeted therapeutic strategies in rheumatoid arthritis
- From parasite chromatin to host immune reprogramming: linking developmental state, effector regulation, and persistence in Toxoplasma gondii
- Radiation-induced oral mucositis as an immune hub: from innate immune sensing to adaptive immune dysregulation
- T cell–driven venetoclax resistance in chronic lymphocytic leukemia: in vivo preclinical activity of opaganib
- Mapping the immune microenvironment of KIT- and PDGFRA-mutant GISTs reveals genotype-specific immune infiltration and TKI-induced remodeling
- Pathogen-mediated selection and phylogeny shape MHC architecture in 33 bat genomes
- Case Report: Diagnostic dilemma: rebound thymic hyperplasia mimicking mediastinal relapse following chemoimmunotherapy in pediatric jejunal Burkitt lymphoma
- Gut bacterial lauroyl tryptamine reduces GPR183-associated inflammatory responses in human macrophages and T cells in vitro
- Explainable machine learning using pretreatment complete blood count parameters and demographic characteristics for gastric cancer risk stratification: a temporal validation study
- Editorial: Chemoresistance and immunotherapy in solid tumors
- A multicohort proteomics-based machine learning score (MASHPredict) for noninvasive diagnosis and long-term prognostication of metabolic dysfunction-associated steatohepatitis
- In vivo monitoring of polymorphonuclear myeloid-derived suppressor cells in experimental rheumatoid arthritis
- Rethinking immunotherapy sequencing in multiple myeloma: a conceptual adaptive immunotherapy sequencing model
- Compound heterozygous RHCE null genotype underlying D−− phenotype in a Chinese pregnant woman: molecular characterization and sequential transfusion strategy
- An oral-origin Streptococcus salivarius associated with schizophrenia reshapes intestinal T-cell immunity and promotes IL-17A-dominated inflammation
- Crystalline κ-light-chain proximal tubulopathy in Waldenström macroglobulinemia with an IgA nephropathy pattern: a case report and systematic review
- Leishmania infantum triggers lipid peroxidation and non-canonical cell death in macrophages
- Gut mycobiome dysbiosis in inflammatory bowel disease: a systematic review and meta-analysis
- Enteropathy in inborn and acquired errors of immunity: histological patterns and clinical correlates
- Case Report: A case of postneurosurgery Klebsiella pneumoniae meningitis with longitudinal CSF cytokine profiling and combined intrathecal therapy