Nerve injuries can affect the entire immune system, study finds
Nerve injuries can have long-lasting effects on the immune system that appear to differ between males and females, according to preclinical research from McGill University.
Immunology news
From blood to solid tumors: A new way to power up CAR T cell therapy
Chimeric Antigen Receptor (CAR) T cell therapies have revolutionized cancer treatment—but so far, their success has been largely limited to blood cancers. Solid tumors, which account for around 90% of all adult cancers, remain a major challenge because…
Meat allergy caused by tick bites becoming more common in US, experts say
A once-rare meat allergy caused by tick bites is dramatically increasing across the United States, researchers say.
Innovative surfaces to rapidly load bone implants with antibiotics
Infectious complications are not uncommon after implant placement. The risk is higher in heavily contaminated wounds, which are particularly common in war zones such as Ukraine, where many bone injuries require treatment. Researchers at the Fraunhofer …
Mapping the heart: How cells coordinate repair after heart attack
Over the course of evolution, the human heart has largely lost its ability to regenerate. Our distant ancestors were not afflicted by heart attacks—a condition that emerged primarily with modern lifestyles marked by poor diet, obesity, and other cardio…
VEXAS syndrome research reveals overactive bone marrow stem cells may drive inflammation
Researchers at Memorial Sloan Kettering Cancer Center (MSK) have developed some of the first robust laboratory models of a confounding adult-onset inflammatory disease called VEXAS syndrome—shedding new light on its mechanisms and laying the groundwork…
Turning on an immune pathway in tumors could lead to their destruction
By stimulating cancer cells to produce a molecule that activates a signaling pathway in nearby immune cells, MIT researchers have found a way to force tumors to trigger their own destruction.
Mitochondrial protein represents promising target for autoimmune disease treatment
A new study led by Swansea University has revealed a new way to potentially treat certain autoimmune diseases by targeting a protein that helps regulate energy production in immune cells.
How a tiny RNA molecule in the kidney triggers a deadly autoimmune disease
Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally occurring RNA molecule in the kidney activates a mutated immune receptor, triggering a chain reaction.
Antibody therapy foils pancreatic cancer’s sugar-based disguise to reawaken immune system
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have uncovered a novel explanation for that resistance: Pancreatic tumors use a sugar-based disguise to hide from the i…