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CCR5 and CCL5 in metastatic colorectal cancer

7 de May de 2024 by Schlechter, B. L., Stebbing, J.

The CCR/L5 axis is known for its role in immune regulation in a variety of settings and has been shown to have dichotomous functions in cancer, influencing both tumor progression and immune responses. Battaglin et al investigated its role using genomi…

Categories Journal for ImmunoTherapy of Cancer, Open access, Commentary/Editorials, Publicaciones Tags Journal for ImmunoTherapy of Cancer

Phase 1 first-in-human dose-escalation study of ANV419 in patients with relapsed/refractory advanced solid tumors

3 de May de 2024 by

Patients with advanced cancer, previously treated with immune checkpoint blockade therapy, may retain residual treatment when undergoing the initial infusion of experimental monotherapy in phase 1 clinical trials. ANV419, an antibody-cytokine fusion p…

Categories Journal for ImmunoTherapy of Cancer, Open access, Commentary/Editorials, Publicaciones Tags Journal for ImmunoTherapy of Cancer

Immunotherapy-based regimens for patients with EGFR-mutated non-small cell lung cancer who progressed on EGFR-TKI therapy

17 de April de 2024 by Qin, B.-D., Jiao, X.-D., Yuan, L.-Y., Wu, Y., Ling, Y., Zang, Y.-S.

Abstract

Categories Journal for ImmunoTherapy of Cancer, Open access, Commentary/Editorials, Publicaciones Tags Journal for ImmunoTherapy of Cancer

Do galectins serve as soluble ligands for immune checkpoint receptors?

10 de April de 2024 by Torres, N. I., Baudou, F. G., Scheidegger, M. A., Dalotto-Moreno, T., Rabinovich, G. A.

Abstract

Categories Journal for ImmunoTherapy of Cancer, Open access, Commentary/Editorials, Publicaciones Tags Journal for ImmunoTherapy of Cancer

Targeting of netrin-1 by monoclonal antibody NP137 inhibits the EMT in cancer

5 de April de 2024 by Xia, X., Yin, K., Wang, S.

Abstract

Categories Journal for ImmunoTherapy of Cancer, Open access, Commentary/Editorials, Publicaciones Tags Journal for ImmunoTherapy of Cancer

SITC Clinical Immuno-Oncology Network (SCION) commentary on measurement and interpretation of essential biomarkers in early clinical trials

22 de March de 2024 by

Abstract

Categories Journal for ImmunoTherapy of Cancer, Open access, Commentary/Editorials, Publicaciones Tags Journal for ImmunoTherapy of Cancer

Key role of CD4+ T cells in determining CD8 function during CAR-T cell manufacture

14 de March de 2024 by Melenhorst, J. J., Oliveira, B. C.

Abstract

Categories Journal for ImmunoTherapy of Cancer, Open access, Commentary/Editorials, Publicaciones Tags Journal for ImmunoTherapy of Cancer

Suppressive effects of obesity on NK cells: is it time to incorporate obesity as a clinical variable for NK cell-based cancer immunotherapy regimens?

14 de March de 2024 by Canter, R. J., Judge, S. J., Collins, C. P., Yoon, D. J., Murphy, W. J.

Abstract

Categories Journal for ImmunoTherapy of Cancer, Open access, Commentary/Editorials, Publicaciones Tags Journal for ImmunoTherapy of Cancer

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