Abdulrahman, Z., Slieker, R. C., McGuire, D., Welters, M. J. P., van Poelgeest, M. I. E., van der Burg, S. H.

Single-cell spatial transcriptomics unravels cell states and ecosystems associated with clinical response to immunotherapy

13 de March de 2025 by Abdulrahman, Z., Slieker, R. C., McGuire, D., Welters, M. J. P., van Poelgeest, M. I. E., van der Burg, S. H.

Background
The tumor microenvironment (TME) is a complex and dynamic ecosystem that is known to influence responses to immunotherapy. We leveraged single-cell spatial transcriptomics to systematically dissect the intricate complexity of the TME, in pa…