Nature Reviews Immunology, Published online: 30 June 2025; doi:10.1038/s41577-025-01205-xMaternal obesity during pregnancy promotes a form of fatty liver disease in offspring that is dependent on HIF1α-mediated rewiring of Kupffer cell…
Nature Reviews Immunology, Published online: 27 June 2025; doi:10.1038/s41577-025-01187-wThe vasculature that forms in tumours and supports tumour growth is abnormal and limits T cell entry into tumours. Here, the authors review how th…
Nature Reviews Immunology, Published online: 26 June 2025; doi:10.1038/s41577-025-01185-yIn this Review the authors explain how different routes of exposure to food antigens can contribute to the development of food allergies. They dis…
Nature Reviews Immunology, Published online: 25 June 2025; doi:10.1038/s41577-025-01202-0A preprint by Srivastava et al. reports that C19S modification of insulin, which occurs in response to a stressed microenvironment, promotes pro-i…
Nature Reviews Immunology, Published online: 24 June 2025; doi:10.1038/s41577-025-01201-1White et al. show that microbiota-specific T cells are licensed by gut inflammation to infiltrate the central nervous system, where cross-reactivi…
Nature Reviews Immunology, Published online: 18 June 2025; doi:10.1038/s41577-025-01191-0During pregnancy, innate immune mechanisms at the maternal–fetal interface are important for protecting the developing fetus from pathogens. Howev…
Nature Reviews Immunology, Published online: 16 June 2025; doi:10.1038/s41577-025-01193-yIron is crucial for cellular metabolism, but its availability varies greatly within and between individuals and populations. This Review highlight…
Nature Reviews Immunology, Published online: 13 June 2025; doi:10.1038/s41577-025-01192-zT cells have an essential role in immune responses to Mycobacterium tuberculosis, but the mechanisms by which they may provide protective immunity…
Nature Reviews Immunology, Published online: 12 June 2025; doi:10.1038/s41577-025-01188-9This Perspective explores how the gut microbiota influences the function and heterogeneity of microglia, highlighting their roles in neurological …
Nature Reviews Immunology, Published online: 12 June 2025; doi:10.1038/s41577-025-01198-7A preprint by Li et al. presents a comprehensive pan-cancer atlas of tumour-specific peptides that markedly expands the known tumour antigen reper…
