Nature Reviews Immunology, Published online: 12 May 2026; doi:10.1038/s41577-026-01310-5CD8+ T cells infiltrating the kidneys contribute to lupus nephritis by retaining cytotoxic functions despite appearing to be terminally differentia…
Nature Reviews Immunology, Published online: 11 May 2026; doi:10.1038/s41577-026-01311-4Macrophages continuously ‘nibble’ healthy neighbouring cells, capturing minute amounts of cytosolic material that are preserved in specialized vesi…
Nature Reviews Immunology, Published online: 08 May 2026; doi:10.1038/s41577-026-01305-2T cells integrate signals from self-ligands not only during thymic development but also as they circulate through secondary lymphoid organs. These …
Nature Reviews Immunology, Published online: 06 May 2026; doi:10.1038/s41577-026-01309-yHu et al. report that activated T cells can enhance antigen processing and presentation in tumour cells and dendritic cells through DNA transfer by…
Nature Reviews Immunology, Published online: 06 May 2026; doi:10.1038/s41577-026-01304-3This Review compares the structure–function relationships of the apoptosome, inflammasomes and PIDDosome, which are the three main platforms activa…
Nature Reviews Immunology, Published online: 05 May 2026; doi:10.1038/s41577-026-01308-zA preprint by Chen et al. identifies Dusp5 and Zfp219 as regulators of age-associated T cell dysfunction in the tumour microenvironment.
Nature Reviews Immunology, Published online: 05 May 2026; doi:10.1038/s41577-026-01303-4This Review from Shokrollah Elahi considers how erythroid cells — including erythroid progenitors and precursors and mature red blood cells — can m…
Nature Reviews Immunology, Published online: 01 May 2026; doi:10.1038/s41577-026-01306-1No matter how small the possibility, or how inconvenient the topic, scientists must maintain the humility to acknowledge that we could be wrong. Ou…
Nature Reviews Immunology, Published online: 23 April 2026; doi:10.1038/s41577-026-01291-5What is unique about the immune system of people who live to extreme old age? Here the authors describe that centenarians may achieve such longev…
Nature Reviews Immunology, Published online: 22 April 2026; doi:10.1038/s41577-026-01294-2This Review discusses the diverse lymphocyte responses that occur against Leishmania parasites. In particular, the authors highlight how these im…
