AQP4 antibody-induced astrocyte injury reshapes CNS immune architecture in a combined EAE–AQP4-IgG model of neuromyelitis optica spectrum disorder
Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) are inflammatory autoimmune diseases of the central nervous system (CNS) that share demyelinating features but differ fundamentally in pathogenesis. The discovery of neuromyelit…