Haploidentical and MHC-identical cells exhibit broadly similar immune reconstitution kinetics, with some compartment-specific differences, following hematopoietic cell transplantation in a murine model of severe combined immunodeficiency
IntroductionImmune reconstitution following HLA-haploidentical hematopoietic cell transplantation (Haplo-HCT) is often delayed compared with HLA-identical transplantation, which frequently poses clinical challenges. The reasons for these differences in…