Rui Fan – InmunoES

Metallothionein-2A licenses an S100A8 alarmin program to drive epithelial-mesenchymal transition in pulmonary fibrosis

22 de October de 2026 by Rui Fan

BackgroundPulmonary fibrosis (PF) is a progressive interstitial lung disease driven in part by epithelial–mesenchymal transition (EMT), but the upstream epithelial regulators remain undefined, and conventional screens rarely separate causal drivers fro…

KHDRBS1 as a novel prognostic signaling biomarker influencing hepatocellular carcinoma cell proliferation, migration, immune microenvironment, and drug sensitivity

10 de April de 2024 by Rui Fan

BackgroundHuman tumors pose significant challenges, with targeted therapy against specific molecular targets or signaling pathways being a mainstay alongside surgical resection. Previous studies have implicated KHDRBS1 in the oncogenesis of certain hum…