Phenotypic and immunological profile divergence between SLE-associated myelitis and SLE-NMOSD overlap syndrome: a retrospective case series

BackgroundSystemic lupus erythematosus-associated myelitis (SLE-AM) is a devastating neuroimmunological complication. Increasing evidence suggests that myelitis occurring in patients with SLE is heterogeneous and may include non-overlap SLE-AM and SLE-…

Serologic biomarker discovery for differentiating Lyme disease from diseases with similar clinical symptoms using broad profiling of antibody binding

IntroductionLyme disease (LD) is a tick-borne disease that is a substantial public health burden with estimated about 0.5 million new cases per year in the US and increasing incidence. Differentiating Lyme disease, especially in its early stages, from …

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