Compound heterozygous RHCE null genotype underlying D−− phenotype in a Chinese pregnant woman: molecular characterization and sequential transfusion strategy
The D−− phenotype is an extremely rare Rh blood group variant with absence of C, c, E, and e antigens but preserved D expression, predisposing to anti-Rh17 alloimmunization and hemolytic disease of fetus and newborn (HDFN). We report a 25-year-old Chin…