FTO-mediated demethylation of PRKCB mRNA activates NF-κB to trigger alveolar fibrin deposition in ARDS
BackgroundAcute Respiratory Distress Syndrome (ARDS) is characterized by alveolar fibrin deposition, driven by dysregulated hypercoagulation and impaired fibrinolysis. Although alveolar epithelial type II (AEC II) cells contribute to this imbalance by …