Integrating multi-omics and machine learning to reveal IL1R2-driven macrophage-fibroblast spatial interactions in polycyclic aromatic hydrocarbon-induced pulmonary fibrosis
BackgroundPolycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental toxicants, yet the toxicological mechanisms by which they induce idiopathic pulmonary fibrosis (IPF) remain poorly understood. This study aims to systematically elucidate th…