Lu Qiao
Plasticity and antigen presentation by group 3 innate lymphoid cells in colorectal cancer
Colorectal cancer (CRC) develops within a mucosal ecosystem where the microbiota, epithelial barrier, and group 3 innate lymphoid cells (ILC3) jointly shape immune tone. ILC3 plasticity spans both tissue-protective and inflammatory states, and MHC II-d…
HMGA2 interacts with KAT6A to regulate MMPs chromatin architecture and promote triple-negative breast cancer metastasis
BackgroundTriple-negative breast cancer (TNBC), the most lethal breast cancer subtype, demonstrates poor prognosis due to its high rates of metastasis, recurrence, and mortality. The metastatic potential in TNBC patients serves as a critical determinan…