Bo Wang BackgroundOsteoarthritis (OA) is increasingly recognized as a whole-joint disorder in which mechanical stress, cellular mechanosensing, and inflammatory responses interact across joint tissues. Although OA mechanoinflammation has attracted growing atte…
The immunomodulatory potential of Lycium barbarum polysaccharides (LBP) is well-established, yet the intricate structure-activity relationships (SAR) underlying these effects require clarification to advance therapeutic applications. This review synthe…
Astragalus Polysaccharide (APS), the primary bioactive component of Astragalus, exhibits multi-faceted immunomodulatory properties. Its efficacy stems not from broad, non-specific stimulation but from the precise engagement of a network of cell surface…
Cancer stem cells (CSCs) represent a small subset of tumor cells populations characterized by their ability to self-renew and differentiate. These cells are often considered resistant to chemotherapy, radiotherapy, and immunotherapy, playing a crucial …
Renal cell carcinoma (RCC), particularly the clear-cell subtype (ccRCC), accounts for 75-85% of kidney cancers and exhibits distinct genetic and biological heterogeneity. While surgical resection remains the mainstay of treatment for localized ccRCC, t…
BackgroundThe Naples Prognostic Score (NPS) is innovatively constructed to comprehensively evaluate the inflammatory and nutritional status according to several basic blood examinations. This study aimed to investigate the correlation between NPS and l…
