inmunoadmin

(A) BMMCs are substantially more resistant to oxygen deprivation than neurons, microglia, oligodendrocytes, astrocytes, and fibroblasts. (B) Role of SHIP-1 in primary mouse bone marrow mast cells’ hypoxia response. Under hypoxia, SHIP-1 induces cytokine release. SHIP1 restrains hypoxia/reoxygenation-induced cytokine secretion in BMMCs via the RAS/ RAF, HIF1α, and PI3K/AKT pathways. The graphical abstract was prepared … Read more

The graphical abstract illustrates MTEX-driven reprogramming of CD3(+) T cells in patients with melanoma. ABSTRACT Small extracellular vesicles (sEV) released by T cells play a key role in immune regulation. Immune capture with anti-CD3 antibodies was used to isolate and study T cell-derived CD3(+)sEV from the plasma of patients with melanoma (MPs) or healthy donors … Read more

Sex-biased synovial immunity features enhanced CCL3/CCL4-mediated CD8+ T-cell infiltration in female early-onset RA. This immune signature correlates with disease activity and fuels joint inflammation in female ERA patients. ABSTRACT Rheumatoid arthritis (RA) exhibits significant sexual dimorphism, with females being two to three times more susceptible than males. CD8+ T cells are key effector immune cells … Read more

European Journal of Immunology, Volume 56, Issue S4, September 2026.