Preliminary analysis of the proportions and characteristics of dual TCR T cells and dual BCR B cells in echinococcus granulosus-infected mice using scRNA+TCR+BCR-seq

IntroductionCystic echinococcosis (CE) is a zoonotic parasitic disease caused by Echinococcus granulosus, and the T and B cell responses and regulatory mechanisms in CE remain unclear.MethodsIn this study, we analyzed the data of peripheral blood and s…

The “serine code” of metabolic reprogramming: multidimensional roles of the serine synthesis pathway in tumors and novel breakthroughs for targeted therapy

As a pivotal contributor to tumor metabolism following glucose and glutamine, serine plays a crucial role in the metabolic network of tumors via its de novo synthesis pathway (SSP). The SSP is aberrantly activated in a variety of malignant tumors and p…

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