Immune-checkpoint blockade and candidate predictive biomarkers in HIV-negative Kaposi sarcoma: current evidence and a practical research framework
Kaposi sarcoma (KS) is a KSHV/HHV-8-driven vascular neoplasm with heterogeneous HIV-negative epidemiological settings. Immune-checkpoint blockade is biologically plausible, but direct clinical evidence remains limited to a small, non-comparative phase …