BackgroundBrucellosis can resemble lymphoma when lymphadenopathy accompanies cytopenias and systemic inflammation. Associated secondary haemophagocytic lymphohistiocytosis (HLH) adds to the diagnostic difficulty.Case presentationA 68-year-old man prese…
Dupilumab blocks interleukin (IL)-4 and IL-13 signaling and is effective for type 2 inflammatory diseases, including atopic dermatitis and prurigo nodularis. Paradoxical psoriasiform eruptions and, less commonly, new-onset or worsening vitiligo have be…
Immune checkpoint inhibitor (ICI) have substantially extended survival in patients with extensive-stage small-cell lung cancer (ES-SCLC), yet they also carry the risk of life-threatening immune-related adverse events (irAEs). Clinical experience in man…
Rituximab (RTX) can improve outcomes in children with frequently relapsing or steroid-dependent nephrotic syndrome, although a marked reduction in circulating B cells does not invariably coincide with renal remission. We report a girl who developed fre…
BackgroundBullous pemphigoid (BP) may occur during interleukin-17A inhibitor therapy in patients with psoriasis. Most reported cases have focused on BP onset and short-term management, with limited information on long-term outcomes and subsequent targe…
PurposeTo report a case of Staphylococcus epidermidis endophthalmitis in chronic ocular graft-versus-host disease, refractory to empirical broad-spectrum antibiotics, rapidly identified by metagenomic next-generation sequencing of aqueous humor, and su…
Eosinophilic granulomatosis with polyangiitis (EGPA) rarely involves the central nervous system and may closely resemble inflammatory demyelinating disease. We report a 32-year-old woman with adult-onset asthma and recurrent sinusitis who presented wit…
BackgroundAutoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a rare autoimmune inflammatory disease of the central nervous system that frequently mimics infectious meningoencephalitis. Because its clinical presentation, cerebrospinal f…
A 47-year-old woman with poorly controlled diabetes developed acute fever, headache, seizures, and progressive confusion during an admission for glycemic management. Neurological examination showed mild meningeal signs, and brain MRI demonstrated diffu…
Light-chain proximal tubulopathy (LCPT) is a rare renal manifestation of monoclonal gammopathy that is exceptionally uncommon in Waldenström macroglobulinemia (WM). We report a case of crystalline κ-LCPT in WM and conduct a literature review of WM-asso…
