BackgroundPediatric sporadic Burkitt lymphoma (BL) typically presents with gastrointestinal involvement; primary mediastinal disease is exceedingly rare. Rebound thymic hyperplasia (RTH) is a benign regenerative process following chemotherapy that can …
BackgroundAcrodermatitis continua of Hallopeau (ACH) is a relatively rare chronic skin disorder often associated with immune system abnormalities. Conventional systemic therapies and biologics have limited efficacy and are prone to relapse, highlightin…
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) results from severe ADAMTS13 deficiency and may relapse despite modern therapy, with survival exceeding 95% in contemporary cohorts. We report the case of a 43-year-old patient with multiple cl…
BackgroundAlopecia areata (AA) is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hashimoto’s thyroiditis (HT) and Sjögren’s syndrome (SS) are common systemic autoimmune disorders that ma…
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy and primarily caused by abnormalities in the regulation of the alternative complement pathway, with triggers including infection, pregnancy, surgery and autoimmune disorders like…
Anti-mitochondrial M2 antibodies (AMA-M2) are a serologic hallmark of primary biliary cholangitis (PBC), but in inflammatory myopathy they have also been associated with chronic muscle disease, cardiac involvement, and respiratory muscle weakness. We r…
Granulomatous lung disease caused by cytomegalovirus (CMV) has not been described in immunocompetent infants. We report a 5-month-old boy, born at 31+5 weeks of gestation, with a 2-month history of isolated cough and normal growth. Contrast-enhanced ch…
BackgroundNeuro-Behçet disease (NBD) is a rare but potentially disabling manifestation of Behçet disease (BD). Its heterogeneous neurological presentation can mimic central nervous system infection, cerebrovascular disease, inflammatory demyelination o…
Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare and severe phenotype within stiff-person spectrum disorders (SPSD), frequently associated with glycine receptor antibodies (GlyR-Ab). Because typical rigidity and stimulus-sensi…
IntroductionCentral serous chorioretinopathy (CSCR) is characterized by retinal pigment epithelium dysfunction and choroidal hyperpermeability. Beyond established associations such as psychosocial stress and corticosteroid exposure, experimental and ep…
