Jie Li Tumors evade macrophage-mediated clearance through mechanistically distinct but functionally convergent anti-phagocytic pathways. This review examines canonical and emerging receptor–ligand “don’t eat me” axes, Siglec-dependent glyco-inhibitory checkpo…
ObjectiveThis study investigated whether adipose-derived mesenchymal stem cells-exosomes (ADMSC-Exo) alleviate lipopolysaccharide (LPS)-induced acute lung injury (ALI) by regulating NLRP3 inflammasome-mediated macrophage M1 polarization and pyroptosis …
ObjectiveGlioma is the most common and aggressive primary intracranial tumor. Its clinical management is substantially hindered by the blood–brain barrier (BBB) and the immunosuppressive tumor microenvironment (TME). This study aimed to construct PD-1-…
BackgroundImmune checkpoint inhibitors (ICIs) can cause rare but clinically important immune-related neuromuscular adverse events. Early warning signals for ICI-associated neuromuscular toxicity remain poorly defined, particularly after PD-1 inhibitor …
Autoimmune diseases arise from immune system dysfunction, in which immune cells erroneously attack the body’s own tissues, leading to systemic disorders or localized pathological changes. The number of patients with autoimmune diseases is gradually inc…
