Complement-amplified thrombotic microangiopathy in systemic lupus erythematosus and lupus nephritis: a systematic review of 78 reported patients

BackgroundThrombotic microangiopathy (TMA) complicating systemic lupus erythematosus (SLE) and lupus nephritis (LN) spans immune thrombotic thrombocytopenic purpura, anti-phospholipid-associated microangiopathy, secondary endothelial injury, and comple…

CAR-based cellular therapy for refractory systemic lupus erythematosus: an overlap-controlled systematic review

ObjectivesTo define the current evidence for CAR-based cellular therapy in relapsed or refractory systemic lupus erythematosus (SLE) by resolving overlapping reports and synthesising patient-level phenotype, safety and efficacy data. The primary purpos…

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