Yan Dong – InmunoES

Integrative single-cell and bulk transcriptomics with reverse network pharmacology prioritizes macrophage-associated candidate genes in Lyme arthritis

13 de October de 2026 by Yan Dong

IntroductionLyme arthritis (LA) involves complex immune dysregulation, and macrophages contribute centrally to persistent joint inflammation. However, synovial macrophage heterogeneity and its potential relevance to therapeutic intervention remain inco…

Targeting pathogenic immune cells in rheumatoid arthritis: emerging immunotherapeutic frontiers

5 de October de 2026 by Yan Dong

Rheumatoid arthritis (RA) is a persistent autoimmune condition that predominantly affects the joints resulting in inflammation, pain and progressive disability. Immunological imbalance, especially the stimulation of pathogenic immune cells, including T…

Perspective on the integration of radiomics and spatial omics in the analysis of the tumor microenvironment of bladder cancer and prospects for precision diagnosis and treatment

8 de July de 2026 by Yan Dong

Bladder cancer, a common malignant tumor of the urinary system, possesses a highly heterogeneous tumor immune microenvironment that critically influences disease progression, treatment response, and patient prognosis. The limitations of traditional tis…