Ying Liu BackgroundMethotrexate (MTX)-induced pulmonary fibrosis (MTX-PF) is the most severe and frequently irreversible manifestation of MTX pulmonary toxicity, yet the molecular target and signaling circuitry linking drug exposure to fibrosis remain undefined…
BackgroundTraditional research on the female reproductive tract (FRT) microbiome has focused on the dominance of bacteria, particularly Lactobacillus, as a marker of health. This bacteriocentric paradigm, however, cannot fully explain clinical enigmas …
Osteoarthritis (OA) is the most prevalent chronic degenerative joint disorder worldwide, characterized by progressive cartilage degradation, subchondral bone remodeling, synovial inflammation, and impaired mobility. Growing evidence has established mit…
The initial defense against pathogens is the innate immunity, which is characterized by rapidity and the broad-spectrum operation that facilitates the rapid identification and removal of the invasion by microorganisms. The determination of innate immun…
We here report the first case of subacute combined degeneration (SCD)-mimic accompanying adaptor protein-3B2 (AP3B2) antibody, expanding the clinical spectrum of AP3B2 antibody-associated disorders. A 55-year-old woman presented with progressive limb n…
