- Markers predicting lymphoma development in Sjögren disease: current status and future perspectivesby inmunoadminCurr Opin Immunol. 2026 Jan 8;99:102717. doi: 10.1016/j.coi.2025.102717. Online ahead of print. ABSTRACT We aim to present recent advancements in predictive markers for lymphomagenesis in SjD, concisely organize existing knowledge, and identify corresponding unmet needs and future perspectives. First, we briefly describe the mechanisms of lymphomagenesis in SjD. Followingly, the reasons justifying the importance of … Read more
- Emerging diagnostic techniques in sarcoidosis: a path forwardby inmunoadminCurr Opin Immunol. 2026 Jan 8;99:102716. doi: 10.1016/j.coi.2025.102716. Online ahead of print. ABSTRACT Sarcoidosis is a complex and heterogenous disease of which the diagnosis is based on clinical and radiological findings, histopathology showing non-caseating granulomas, and exclusion of other granulomatous diseases. Several tools are well established in the diagnostic pathway, such as pulmonary function tests, … Read more
- Trained ILC2 prevent IL-17-associated lung injury during helminth infection through a serotonin-dependent mechanism. Ulrich Membe Femoeby inmunoadminMucosal Immunol. 2026 Jan 7:S1933-0219(26)00002-4. doi: 10.1016/j.mucimm.2026.01.002. Online ahead of print. ABSTRACT Type 2 cytokinerelease promotes wound healing and helminth clearance, but it remains unclearwhethergroup 2 innate lymphocytes (ILC2s) and T-helper2 cells (TH2) cells have functionally distinctroles during anamnestic immunity. This study demonstrates that ILC2 can prevent re-infection andlimit tissue injury caused by the helminthNippostrongylus … Read more
- Decoding brain border immunity to enable future therapeutic avenues. Lien Van Hoeckeby inmunoadminTrends Immunol. 2026 Jan 8:S1471-4906(25)00315-1. doi: 10.1016/j.it.2025.12.007. Online ahead of print. ABSTRACT The brain is no longer viewed as immunologically isolated but as an organ surrounded by dynamic border compartments that coordinate surveillance, drainage, and communication with the periphery. Key interfaces – including the meninges, blood-brain barrier, choroid plexus (ChP), and skull bone marrow – … Read more
- Pseudomonas aeruginosa exacerbates bladder cancer progression by activating cancer-driven immunosuppressionby inmunoadminCancer Immunol Res. 2026 Jan 9. doi: 10.1158/2326-6066.CIR-25-0873. Online ahead of print. ABSTRACT Pseudomonas aeruginosa infection is still a serious problem among immunocompromised patients who have advanced urinary tract malignancies, yet the impact of P. aeruginosa on disease progression remains poorly defined. Here, we show that urinary tract infections (UTI) caused by P. aeruginosa exacerbated … Read more