Trends in Immunology

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  • Outcome measures in systemic lupus erythematosus
    Curr Opin Immunol. 2026 Apr 30;100:102782. doi: 10.1016/j.coi.2026.102782. Online ahead of print. ABSTRACT Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by fluctuating multisystem involvement, relapsing-remitting activity, and substantial risk of irreversible organ damage. Standardized disease activity indices have facilitated clinical trials and research, yet integration into clinical practice has not occurred for … Read more
  • Scaling immunity: sickness as a host defense strategy. A Clare Sparling
    Trends Immunol. 2026 Apr 30:S1471-4906(26)00076-1. doi: 10.1016/j.it.2026.03.015. Online ahead of print. ABSTRACT Sickness, or sickness behavior, is a state of altered physiology and behavior generated by the brain-immune axis during infection, which is generally assumed to contribute to host defense. Here, we examine this assumption by framing sickness as organismal-scale immunity and explore predicted parallels … Read more
  • Freedom of scientific inquiry: reclaiming space for controversy
    Nature Reviews Immunology, Published online: 01 May 2026; doi:10.1038/s41577-026-01306-1No matter how small the possibility, or how inconvenient the topic, scientists must maintain the humility to acknowledge that we could be wrong. Ou…
  • B cells gone broad: A deep dive into SARS-CoV-2 antibody breadth
    Science Immunology, Volume 11, Issue 119, May 2026.
  • A parasite partner for regulatory affairs
    Science Immunology, Volume 11, Issue 119, May 2026.
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