- NKG2A+ NK cell cytotoxicity of Epstein-Barr virus infected B cells is mediated through the NKG2D and NKp30 activating receptorsby inmunoadminJ Immunol. 2026 Feb 9;215(2):vkaf366. doi: 10.1093/jimmun/vkaf366. ABSTRACT Epstein-Barr virus (EBV) is a human γ-herpesvirus that establishes latency and lifelong infection in B cells. Failure to control latent EBV infection can result in a variety of malignancies, including lymphoproliferative diseases. Studies have implicated natural killer (NK) cells as critical in the host defense against lytic … Read more
- Persistent Gut-Immune Axis dysregulation in long-term Post-COVID Syndrome: Insights from a prospective, observational, cross-sectional case-control study. Max Augustinby inmunoadminMucosal Immunol. 2026 Mar 5:S1933-0219(26)00026-7. doi: 10.1016/j.mucimm.2026.03.002. Online ahead of print. ABSTRACT Post-COVID syndrome (PCS) is a complex condition that can emerge after recovery from SARS-CoV-2 infection, even in young, healthy individuals with mild acute illness. While the underlying mechanisms remain unclear, viral persistence and immune dysregulation are considered key contributors. This study investigates whether … Read more
- PD-L1 cell-intrinsic signals limit immune activation during cutaneous vaccinia virus infectionby inmunoadminJ Immunol. 2026 Feb 9;215(2):vkaf368. doi: 10.1093/jimmun/vkaf368. ABSTRACT Negative T-cell regulation through programmed cell death 1 (PD-1)-programmed death ligand 1 (PD-L1) ligation is well described during viral infection; however, our understanding of the contribution of PD-L1-intrinsic signaling to antiviral immunity is limited. Herein, we show that mutation of the PD-L1 intracellular domain results in a … Read more
- Characterisation of a Leaky Splice-Site Mutation Associated with Phenotypic Diversity in Two Unrelated Patients with ARPC1B Deficiencyby inmunoadminJ Clin Immunol. 2026 Mar 7. doi: 10.1007/s10875-026-02002-4. Online ahead of print. NO ABSTRACT PMID:41793545 | DOI:10.1007/s10875-026-02002-4
- Prognostic Factors for Sideroblastic Anemia with B-cell Immunodeficiency, Periodic Fevers, and Developmental Delay Due to TRNT1 Gene Mutations: A Case Report and Systematic Reviewby inmunoadminJ Clin Immunol. 2026 Mar 7. doi: 10.1007/s10875-026-02000-6. Online ahead of print. NO ABSTRACT PMID:41795040 | DOI:10.1007/s10875-026-02000-6