- CCR8+ decidual regulatory T cells maintain maternal-fetal immune tolerance during early pregnancy
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Endothelial-driven TGFβ signaling supports lung interstitial macrophage development from monocytes
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Bcl11a maintains hematopoietic stem cell function but accelerates inflammation-driven exhaustion during aging
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Erratum for the Research Article “Anti–immune complex antibodies are elicited during repeated immunization with HIV Env immunogens” by S. Brown et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 10, Issue 106, April 2025.
- Psychological stress increases skin infection through the action of TGFβ to suppress immune-acting fibroblasts
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Foxo1 regulates intestinal tissue–resident memory CD8 T cell biology in an anatomic compartment– and context-specific manner
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- They are what they eat
by Asha Pillai
Science Immunology, Volume 10, Issue 106, April 2025.
- Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia
by Kangzhi Chen and Kevin C. O’Connor
Science Immunology, Volume 10, Issue 106, April 2025.
- Eosinophil innate immune memory after bacterial skin infection promotes allergic lung inflammation
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Brain sensing of metabolic state regulates circulating monocytes
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Skin damage signals mediate allergic sensitization to spatially unlinked antigen
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Immunogenomic cancer evolution: A framework to understand cancer immunosuppression
by Shogo Kumagai, Yusaku Momoi, Hiroyoshi Nishikawa
Science Immunology, Volume 10, Issue 105, March 2025.
- An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- GM-CSF–mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to Aspergillus fumigatus
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- DNMT1 inhibition reprograms T cells to NK-like cells with potent antitumor activity
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- QRICH1 mediates an intracellular checkpoint for CD8+ T cell activation via the CARD11 signalosome
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- ATF4 drives regulatory T cell functional specification in homeostasis and obesity
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Trouble at the border: An invading gut bacterium can break tolerance to self-RNA
by Rachael A. Clarknn
Science Immunology, Volume 10, Issue 105, March 2025.
- MBPeace treaty: How myelin self-peptides broker CNS tolerance
by Isabelle Leo and Etienne Caronnnn
Science Immunology, Volume 10, Issue 105, March 2025.
- Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Dynamic STING repression orchestrates immune cell development and function
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Altered immune landscape of cervical lymph nodes reveals Epstein-Barr virus signature in multiple sclerosis
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Linking vaccine adjuvant mechanisms of action to function
by Elana Ben-Akiva, Asheley Chapman, Tianyang Mao, Darrell J. Irvinennnnnn
Science Immunology, Volume 10, Issue 104, February 2025.
- TRAF3 is critical for initial T follicular helper cell specification via coordination of the IL-6R/IL-2R–BCL6 signaling nexus
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Afraid of needles? Try lotion: Engineering skin commensals for vaccination
by Daniel A. Shapiro and Christopher A. Hunternn
Science Immunology, Volume 10, Issue 104, February 2025.
- IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Molecular determinants of cross-strain influenza A virus recognition by αβ T cell receptors
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Is one lymphocyte’s brake another lymphocyte’s gas?
by Thomas T. Xu and Shiv Pillainn
Science Immunology, Volume 10, Issue 104, February 2025.
- Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Human naïve B cells recognize prepandemic influenza virus hemagglutinins
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Coordinated immune networks in leukemia bone marrow microenvironments distinguish response to cellular therapy
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Architects of immunity: How dendritic cells shape CD8+ T cell fate in cancer
by Vidit Bhandarkar, Teresa Dinter, Stefani Sprangernnn
Science Immunology, Volume 10, Issue 103, January 2025.
- Anti–immune complex antibodies are elicited during repeated immunization with HIV Env immunogens
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- TSLP acts on regulatory T cells to maintain their identity and limit allergic inflammation
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Molecular scalpels dissect new GluN1 hot spots in anti–NMDA receptor encephalitis
by Marianna Spatola and Josep Dalmaunnnnn
Science Immunology, Volume 10, Issue 103, January 2025.
- SNIPR alert! Making T cells more precise killers
by Jonathan Chuck and Laura A. Soltnnn
Science Immunology, Volume 10, Issue 103, January 2025.
- Suppression of thrombospondin-1–mediated inflammaging prolongs hematopoietic health span
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Functional differences between rodent and human PD-1 linked to evolutionary divergence
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- NEK7 phosphorylation amplifies NLRP3 inflammasome activation downstream of potassium efflux and gasdermin D
by Jie Xu, Lingzhi Zhang, Yanhui Duan, Fangyuan Sun, Nouha Odeh, Yuan He, Gabriel Núñeznnn
Science Immunology, Volume 10, Issue 103, January 2025.
- Erratum for the Research Article “GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing” by J. E. Heraud-Farlow et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 9, Issue 102, December 2024.
- Meeting report: Hidden links in autoimmunity
by Mireia Guerau-de-Arellano, Margaret A. Morris, Matthew A. Sherman, Thomas R. Eschnn
Science Immunology, Volume 9, Issue 102, December 2024.
- NK cells restrain cytotoxic CD8+ T cells in the submandibular gland via PD-1–PD-L1
by Samantha M. Borys, Shanelle P. Reilly, Ian Magill, David Zemmour, Laurent Brossaynnnnn
Science Immunology, Volume 9, Issue 102, December 2024.
- Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells
by Seongji Park, Jeonghyun Ahn, Glen N. Barbernnn
Science Immunology, Volume 9, Issue 102, December 2024.
- Extrasinusoidal macrophages are a distinct subset of immunologically active dural macrophages
by inmunoadmin
Science Immunology, Volume 9, Issue 102, December 2024.
- Erratum for the Research Article “Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion” by S. K. Whiteside et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 9, Issue 102, December 2024.
- Crystal structure of the human LAG-3–HLA-DR1–peptide complex
by inmunoadmin
Science Immunology, Volume 9, Issue 102, December 2024.
- Asparagine availability controls germinal center B cell homeostasis
by inmunoadmin
Science Immunology, Volume 9, Issue 102, December 2024.
- Immunopathology in human tuberculosis
by Thomas J. Scriba, Mahlatse Maseeme, Carly Young, Laura Taylor, Alasdair J. Lesliennnnnn
Science Immunology, Volume 9, Issue 102, December 2024.
- The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication
by inmunoadmin
Science Immunology, Volume 9, Issue 102, December 2024.
- It’s the little things in life: Lymph node microniches drive TH2 formation in allergic asthma
by Kelly Butler and Adam Williamsnnnn
Science Immunology, Volume 9, Issue 102, December 2024.
- Removing “flavor” from pathogenic antibodies hits a therapeutic sweet spot
by Dana L. E. Vergoossen and Maartje G. Huijbersnnn
Science Immunology, Volume 9, Issue 102, December 2024.
- A helminth enzyme subverts macrophage-mediated immunity by epigenetic targeting of prostaglandin synthesis
by inmunoadmin
Science Immunology, Volume 9, Issue 102, December 2024.
- MAIT cell plasticity enables functional adaptation that drives antibacterial immune protection
by inmunoadmin
Science Immunology, Volume 9, Issue 102, December 2024.
- Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction
by inmunoadmin
Science Immunology, Volume 9, Issue 101, November 2024.
- A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses
by Yexin Yang, Rebecca S. Treger, Juan Hernandez-Bird, Peiwen Lu, Tianyang Mao, Akiko Iwasakinnnn
Science Immunology, Volume 9, Issue 101, November 2024.
- The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by dendritic cells
by inmunoadmin
Science Immunology, Volume 9, Issue 101, November 2024.
- CAR-ving away OX40L with engineered Tregs
by Jonathan S. Maltzmannnn
Science Immunology, Volume 9, Issue 101, November 2024.
- TAM-ing the beast with IL-34 blockade
by Aron Gyorgypal and Robert M. Anthonynn
Science Immunology, Volume 9, Issue 101, November 2024.
- Kupffer cell reverse migration into the liver sinusoids mitigates neonatal sepsis and meningitis
by inmunoadmin
Science Immunology, Volume 9, Issue 101, November 2024.
- Monocytes and their doppelgängers: An immunological crossroads
by Alexander Mildner and Simon Yonannnn
Science Immunology, Volume 9, Issue 101, November 2024.
- Orientation-dependent CD45 inhibition with viral and engineered ligands
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- Gastrointestinal germinal center B cell depletion and reduction in IgA+ plasma cells in HIV-1 infection
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- Erratum for the Research Article “Circulating KLRG1+ long-lived effector memory T cells retain the flexibility to become tissue resident” by E. D. Lucas et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 9, Issue 100, October 2024.
- Programmable bacteria synergize with PD-1 blockade to overcome cancer cell–intrinsic immune resistance mechanisms
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- Erratum for the Research Article “Initiator cell death event induced by SARS-CoV-2 in the human airway epithelium” by K. Liang et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 9, Issue 100, October 2024.
- The acid-sensing receptor GPR65 on tumor macrophages drives tumor growth in obesity
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- An ILC2-chitinase circuit restores lung homeostasis after epithelial injury
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- Human cytomegalovirus UL18 prevents priming of MHC-E– and MHC-II–restricted CD8+ T cells
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- Contactin-4 suppresses antitumor T cell responses by engaging amyloid precursor protein
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- Oncogenic KRAS drives immunosuppression of colorectal cancer by impairing DDX60-mediated dsRNA accumulation and viral mimicry
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4+ T cell response
by inmunoadmin
Science Immunology, Volume 9, Issue 100, October 2024.
- Tricky Ts play possum to propagate autoimmune disease
by Anjali J. Panicker and Kevin C. O’Connornn
Science Immunology, Volume 9, Issue 100, October 2024.
- Dendritic cells in a pinch: Migration during homeostasis
by Eli C. Olson and Stephanie C. Eisenbarthnnn
Science Immunology, Volume 9, Issue 100, October 2024.
- HDAC3 integrates TGF-β and microbial cues to program tuft cell biogenesis and diurnal rhythms in mucosal immune surveillance
by inmunoadmin
Science Immunology, Volume 9, Issue 99, September 2024.
- Twin study identifies early immunological and metabolic dysregulation of CD8+ T cells in multiple sclerosis
by inmunoadmin
Science Immunology, Volume 9, Issue 99, September 2024.
- Two-dose priming immunization amplifies humoral immunity by synchronizing vaccine delivery with the germinal center response
by inmunoadmin
Science Immunology, Volume 9, Issue 99, September 2024.
- Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation
by inmunoadmin
Science Immunology, Volume 9, Issue 99, September 2024.
- CD4+ T cells with convergent TCR recombination reprogram stroma and halt tumor progression in adoptive therapy
by inmunoadmin
Science Immunology, Volume 9, Issue 99, September 2024.
- Expansion of tumor-reactive CD8+ T cell clonotypes occurs in the spleen in response to immune checkpoint blockade
by inmunoadmin
Science Immunology, Volume 9, Issue 99, September 2024.
- When a double negative is not a positive: Autoantibodies against IL-10 in patients with inflammatory bowel disease
by Colleen M. Noviellonn
Science Immunology, Volume 9, Issue 99, September 2024.
- Pre-vax metabolic clues: Cracking the code to a better dengue vaccine
by Fahima Akther and David R. Martineznn
Science Immunology, Volume 9, Issue 99, September 2024.
- MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles
by inmunoadmin
Science Immunology, Volume 9, Issue 99, September 2024.
- Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity
by inmunoadmin
Science Immunology, Volume 9, Issue 99, September 2024.
- IgE plasma cells are transcriptionally and functionally distinct from other isotypes
by inmunoadmin
Science Immunology, Volume 9, Issue 99, September 2024.
- Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site
by inmunoadmin
Science Immunology, Volume 9, Issue 98, August 2024.
- Immunization with germ line–targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques
by inmunoadmin
Science Immunology, Volume 9, Issue 98, August 2024.
- The promise of priming precursors: Advances in inducing CD4 binding site–directed HIV broadly neutralizing antibodies
by Rama Rao Amarannn
Science Immunology, Volume 9, Issue 98, August 2024.
- PPARβ/δ-orchestrated metabolic reprogramming supports the formation and maintenance of memory CD8+ T cells
by inmunoadmin
Science Immunology, Volume 9, Issue 98, August 2024.
- Mast cell–derived BH4 and serotonin are critical mediators of postoperative pain
by inmunoadmin
Science Immunology, Volume 9, Issue 98, August 2024.
- Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved
by inmunoadmin
Science Immunology, Volume 9, Issue 98, August 2024.
