- Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense
by inmunoadmin
Science Immunology, Volume 11, Issue 118, April 2026.
- The autoantigen TRIM21 assembles proinflammatory immune complexes after lytic cell death
by inmunoadmin
Science Immunology, Volume 11, Issue 118, April 2026.
- Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge
by inmunoadmin
Science Immunology, Volume 11, Issue 118, April 2026.
- The rise of spatial TCR profiling: Emerging technologies and open challenges
by Yinglu Tang and Tao Wang
Science Immunology, Volume 11, Issue 118, April 2026.
- Erratum for the Research Article “A noncanonical cytoplasmic role for BUB1 in restraining DNA damage–induced dsRNA accumulation and sensing within stress granules”
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 118, April 2026.
- Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer
by inmunoadmin
Science Immunology, Volume 11, Issue 118, April 2026.
- Intratumoral Treg cell ablation elicits NK cell–mediated control of CD8 T cell–resistant tumors
by inmunoadmin
Science Immunology, Volume 11, Issue 118, April 2026.
- Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF
by inmunoadmin
Science Immunology, Volume 11, Issue 118, April 2026.
- Copper supports regulatory T cell energetic state to sustain peripheral immune tolerance
by inmunoadmin
Science Immunology, Volume 11, Issue 118, April 2026.
- Claudins interact with LILRB immune inhibitory receptors to promote myeloid immunosuppression in cancer
by inmunoadmin
Science Immunology, Volume 11, Issue 118, April 2026.
- The epitope tax: Antibody feedback and the economics of germinal center competition
by Wallace P. Bezerra and Adam Williams
Science Immunology, Volume 11, Issue 118, April 2026.
- Skull-pting meningeal immunity: Skull bone channels shape neonatal meningeal immune cell trafficking
by Emma N. Barnes and David R. Martinez
Science Immunology, Volume 11, Issue 118, April 2026.
- Intestinal epithelial MHC class II induces encephalitogenic CD4 T cells and initiates central nervous system autoimmunity
by inmunoadmin
Science Immunology, Volume 11, Issue 117, March 2026.
- Palmitate-induced mitochondrial damage restricts histone acetylation in CD8 T cells to impair antitumor immunity
by inmunoadmin
Science Immunology, Volume 11, Issue 117, March 2026.
- Erratum for the Research Article “TCRγ constant usage tunes human γδ T cell antigen sensitivity, thymic programming, and peripheral function”
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 117, March 2026.
- Macrophages restrict tumor immune infiltration by controlling collagen topography
by inmunoadmin
Science Immunology, Volume 11, Issue 117, March 2026.
- Immune mechanisms of congenital Zika syndrome
by Abhay P. S. Rathore and Ashley L. St. John
Science Immunology, Volume 11, Issue 117, March 2026.
- The B cell receptor–mTOR signaling axis restricts the accumulation of lung tissue–resident memory B cells after influenza infection
by inmunoadmin
Science Immunology, Volume 11, Issue 117, March 2026.
- T cell development from expanded hematopoietic progenitors reveals initiation control by Lmo2 and Flt3L priming
by inmunoadmin
Science Immunology, Volume 11, Issue 117, March 2026.
- Inflammatory ILC2s migrate to distal tissues during infection using stage-specific S1P receptors
by inmunoadmin
Science Immunology, Volume 11, Issue 117, March 2026.
- EBV grants B cells a license for immortality in the CNS
by Yoshiaki Yasumizu
Science Immunology, Volume 11, Issue 117, March 2026.
- Identification and characterization of dietary antigens in oral tolerance
by inmunoadmin
Science Immunology, Volume 11, Issue 117, March 2026.
- IgG4 on the dance floor: Partners swapped by Fab-arm exchange
by Ailis Grieshaber and Kevin C. O’Connor
Science Immunology, Volume 11, Issue 117, March 2026.
- Modulating AP-1 enables CAR T cells to establish an intratumoral stemlike reservoir and overcomes resistance to PD-1 blockade
by inmunoadmin
Science Immunology, Volume 11, Issue 117, March 2026.
- Human LFA-1 governs T cell immune surveillance of the skin
by inmunoadmin
Science Immunology, Volume 11, Issue 116, February 2026.
- Divergent ILC3 responses to PDGF-D control mucosal immunity
by inmunoadmin
Science Immunology, Volume 11, Issue 116, February 2026.
- Monocyte-derived IL-10 drives sex differences in pain duration
by inmunoadmin
Science Immunology, Volume 11, Issue 116, February 2026.
- RORγt+ dendritic cells are a distinct lymphoid-derived lineage
by inmunoadmin
Science Immunology, Volume 11, Issue 116, February 2026.
- Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization
by inmunoadmin
Science Immunology, Volume 11, Issue 116, February 2026.
- Erratum for the Research Article “Two-dose priming immunization amplifies humoral immunity by synchronizing vaccine delivery with the germinal center response”
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 116, February 2026.
- Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development
by inmunoadmin
Science Immunology, Volume 11, Issue 116, February 2026.
- TCRγ constant usage tunes human γδ T cell antigen sensitivity, thymic programming, and peripheral function
by inmunoadmin
Science Immunology, Volume 11, Issue 116, February 2026.
- The dark side of the dot: How melanosomes dim T cell activity
by Ruimin Wang and Etienne Caron
Science Immunology, Volume 11, Issue 116, February 2026.
- Aldehyde and seek: Toxic aldehydes drive exhaustion in tumor-infiltrating T cells
by Cait A. McAlindon and Rachael A. Clark
Science Immunology, Volume 11, Issue 116, February 2026.
- Cohesin-mediated chromatin organization controls the differentiation and function of dendritic cells
by inmunoadmin
Science Immunology, Volume 11, Issue 116, February 2026.
- Immunobiology of the serous cavities
by James E. Parkinson, Judith E. Allen, Lucy H. Jackson-Jones
Science Immunology, Volume 11, Issue 116, February 2026.
- Single-cell profiling reveals diverse γδ T cell subsets in ulcerative colitis
by inmunoadmin
Science Immunology, Volume 11, Issue 116, February 2026.
- Cross-species cellular mapping and humanization of Fcγ receptors to advance antibody modeling
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- B cells drive CD4 T cell immunosenescence and age-associated health decline
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- Transient disruption of T cell help impairs germinal center dynamics and memory responses
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- Intestinal epithelial TLR5 signaling promotes barrier-supportive macrophages
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- Structural variation tunes apoptotic responses to drive immune escape in melanoma
by Kyung Lock Kim and Gabriel K. Griffin
Science Immunology, Volume 11, Issue 115, January 2026.
- PTMA safeguards mitochondrial integrity to sustain metabolic function and antitumor activity of CD8 T cells
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- Erratum for the Research Article “T cell receptor–triggered nuclear actin network formation drives CD4+ T cell effector functions” by N. Tsopoulidis et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 11, Issue 115, January 2026.
- The OAS–RNase L pathway: Insights from experiments of nature
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- Mycobacterial α-glucans hijack dectin-1 to facilitate intracellular bacterial survival
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and function
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- Segmented filamentous bacteria reprogramming of alveolar macrophages limits postinfluenza bacterial pneumonia
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- Pathogenic IgE-fated memory B cell responses retain functional plasticity
by inmunoadmin
Science Immunology, Volume 11, Issue 115, January 2026.
- Siglec-F+ neutrophils promote the resolution of acute lung injury through ALOX15 induction
by inmunoadmin
Science Immunology, Volume 10, Issue 114, December 2025.
- Divergent immune responses to commensal bacteria bearing distinct motility signatures
by inmunoadmin
Science Immunology, Volume 10, Issue 114, December 2025.
- CD27 agonism enhances long-lived CD4 T cell vaccine responses critical for antitumor immunity
by inmunoadmin
Science Immunology, Volume 10, Issue 114, December 2025.
- Human OCEL1 senses bacterial infection to unlock inflammatory responses
by inmunoadmin
Science Immunology, Volume 10, Issue 114, December 2025.
- Reaching maturity: Thymic γδ T cell differentiation in mice and humans
by Rúben G. R. Pinheiro and Bruno Silva-Santos
Science Immunology, Volume 10, Issue 114, December 2025.
- Erratum for the Review “The immunology of brain tumors” by L. Bunse et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 10, Issue 114, December 2025.
- Heterogeneity of the intestinal mononuclear phagocyte compartment in health and inflammatory bowel disease
by inmunoadmin
Science Immunology, Volume 10, Issue 114, December 2025.
- Hypoxia-induced EGR1 remodels neutrophils to suppress antitumor immunity
by inmunoadmin
Science Immunology, Volume 10, Issue 114, December 2025.
- Smart chains: Designer antibodies shaped by AI
by Thomas T. Xu and Shiv Pillainn
Science Immunology, Volume 10, Issue 114, December 2025.
- Sugar-coated CAR T for sweeter cell therapies
by Dachuan Dong and Jonathan S. Maltzman
Science Immunology, Volume 10, Issue 114, December 2025.
- Assessing AI’s cognitive abilities for scientific discovery in the field of systems vaccinology
by Lucie Rodriguez-Coffinet, Dmitri Kazmin, Bali Pulendran
Science Immunology, Volume 10, Issue 114, December 2025.
- AI immunologists are here: Are they ready for prime time?
by Jacob Kim, Ao Huang, John S. Tsang
Science Immunology, Volume 10, Issue 114, December 2025.
- Molecular basis for de novo thymus regeneration in a vertebrate, the axolotl
by inmunoadmin
Science Immunology, Volume 10, Issue 114, December 2025.
- Maternal allergy and neonatal RSV infection synergize via FcR-mediated allergen uptake to promote the development of asthma in early life
by inmunoadmin
Science Immunology, Volume 10, Issue 113, November 2025.
- Editorial expression of concern
by Seth Thomas Scanlon
Science Immunology, Volume 10, Issue 113, November 2025.
- Joint profiling of gene expression and chromatin accessibility in pancreatic lymph nodes and spleens in human type 1 diabetes
by inmunoadmin
Science Immunology, Volume 10, Issue 113, November 2025.
- GPR25 promotes the formation of lung and liver tissue-resident memory CD8 T cells
by inmunoadmin
Science Immunology, Volume 10, Issue 113, November 2025.
- An islet-resident macrophage antioxidant program preserves β cell physiology
by inmunoadmin
Science Immunology, Volume 10, Issue 113, November 2025.
- CD21 primes extrafollicular differentiation of autoreactive B cells in a TLR7-driven lupus model
by inmunoadmin
Science Immunology, Volume 10, Issue 113, November 2025.
- Two of a kind, one with MS: Gut microbes tip the balance
by Kevin Champagne-Jorgensen and Jennifer L. Gommerman
Science Immunology, Volume 10, Issue 113, November 2025.
- B cells and dengue: A cat-and-mouse game
by Kritika Dixit and David R. Martinez
Science Immunology, Volume 10, Issue 113, November 2025.
- Characterization of the mammalian prodefinitive angio-hematopoietic lineage
by inmunoadmin
Science Immunology, Volume 10, Issue 113, November 2025.
- B cells targeting parasites capture spatially linked antigens to secure T cell help
by inmunoadmin
Science Immunology, Volume 10, Issue 113, November 2025.
- TH17 cells converted into exTH17 cells sustain rheumatoid-like IL-17–independent inflammatory arthritis
by inmunoadmin
Science Immunology, Volume 10, Issue 113, November 2025.
- Stem-like tissue-resident memory T cells control functional heterogeneity and reactivation of T cell memory in the intestine
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Local activation of mutant RIG-I by short noncoding Y-RNA in the kidney triggers lethal nephritis
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- RNA binding proteins control the G2-M checkpoint of the germinal center B cell
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Mitochondrial and lysosomal signaling orchestrates heterogeneous metabolic states of regulatory T cells
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Lipolysis-microlipophagy cascade regulated by adipose triglyceride lipase drives pathogenic adaptive type 2 immunity
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Anticancer immune responses are hindered by cis interaction of inhibitory checkpoint SIRPα
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Erratum for the Research Article “METTL1-mediated m7G methylation of Sarm1 mRNA promotes macrophage inflammatory responses and multiple organ injury” by C. Hou et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 10, Issue 112, October 2025.
- Germinal center–mediated broadening of B cell responses to SARS-CoV-2 booster immunization
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Taking aim at autoimmunity—Antigen-Fc constructs for mucosal pemphigus hit the mark
by Francesca Beretta and Valentina Damato
Science Immunology, Volume 10, Issue 112, October 2025.
- The immunology of brain tumors
by Lukas Bunse, Theresa Bunse, Michael Kilian, Francisco J. Quintana, Michael Platten
Science Immunology, Volume 10, Issue 112, October 2025.
- The power of the few: RORγt+ dendritic cells promote food-specific peripheral regulatory T cells
by Elise G. Liu and Adam Williams
Science Immunology, Volume 10, Issue 112, October 2025.
- Vaccination-induced T cell responses maintain polyclonality with high antigen receptor avidity
by inmunoadmin
Science Immunology, Volume 10, Issue 112, October 2025.
- Group 2 innate lymphoid cells regulate nociceptive and gait functions of the peripheral nervous system
by inmunoadmin
Science Immunology, Volume 10, Issue 111, September 2025.
- Design of a potent interleukin-21 mimic for cancer immunotherapy
by inmunoadmin
Science Immunology, Volume 10, Issue 111, September 2025.
- Inhibitory immune checkpoints in cancer immunotherapy
by Zhenghai Tang and André Veillette
Science Immunology, Volume 10, Issue 111, September 2025.
- Nuclear polarization to the immune synapse facilitates an early transcriptional burst
by inmunoadmin
Science Immunology, Volume 10, Issue 111, September 2025.
- Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins
by inmunoadmin
Science Immunology, Volume 10, Issue 111, September 2025.
- Single-cell multiomics identifies Tcf1 and Lef1 as key initiators of early thymic progenitor fate
by inmunoadmin
Science Immunology, Volume 10, Issue 111, September 2025.
- Loss-of-function mutations ensure that response to immune checkpoint therapy is NOD2 be denied
by Ana C. Anderson and Manu Rangachari
Science Immunology, Volume 10, Issue 111, September 2025.
- It’s getting hot in here: Heating up the tumor microenvironment with an oral HO-1 inhibitor
by Cait A. McAlindon and Rachael A. Clark
Science Immunology, Volume 10, Issue 111, September 2025.
- METTL1-mediated m7G methylation of Sarm1 mRNA promotes macrophage inflammatory responses and multiple organ injury
by inmunoadmin
Science Immunology, Volume 10, Issue 111, September 2025.
- Enkephalin-producing regulatory T cells in the skin restrain local inflammation through control of nociception
by inmunoadmin
Science Immunology, Volume 10, Issue 111, September 2025.
- DDX55 safeguards naïve T cell homeostasis by suppressing activation-promoting transposable elements
by inmunoadmin
Science Immunology, Volume 10, Issue 111, September 2025.